CHEN Jianye,ZENG Yixin,CHEN Xiaojun,et al.Researches on radioprotective effect of Hu Sheng Bao[J].Chinese Journal of Radiological Medicine and Protection,2000,20(4):273-275
Researches on radioprotective effect of Hu Sheng Bao
Received:September 02, 1999  
DOI:
KeyWords:Astragalus roots  Canoderma lucidum  Radiation injury  Radioprotection
FundProject:美国中华医学基金会(CMB)基金资助项目
Author NameAffiliation
CHEN Jianye 637000 南充, 川北医学院生化教研室 
ZENG Yixin 中山医科大学肿瘤防治中心 
CHEN Xiaojun 中山医科大学肿瘤防治中心 
刘宗 中山医科大学肿瘤防治中心 
潮利国威 中山医科大学肿瘤防治中心 
徐伯平 中山医科大学肿瘤防治中心 
夏云飞 中山医科大学肿瘤防治中心 
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Abstract::
      Objective To research the radioprotective effect of Hu Sheng Bao (HSB) on γ-ray induced injury and to provide an experimental basis for the clinical use of HSB. Methods Mice were treated with three different doses of HSBor normal saline (the control group).All groups were irradiated once with 7.5Gy 60Co γ-rays, and then the difference in survival rates and the changes in blood cells were observed. Results The 30 day survival rate, WBCand PLTcounts of HSB-protected mice were all much higher than those of the control group.The protection factor reached 1.77. Conclusion HSBhas significant anti-radiation effect and can effectively raise the survival rate of mice irradiated with a lethal dose of 60Co γ-rays and it can also reduce the radiation injury of WBCand PLTin mice.
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