| TANG Xicheng,HU Chunzhi,WANG Huijun,et al.Experimental observation of lens damage after low doses of γ-ray irradiation to rabbit eyes[J].Chinese Journal of Radiological Medicine and Protection,2000,20(2):102-104 |
| Experimental observation of lens damage after low doses of γ-ray irradiation to rabbit eyes |
| Received:May 11, 1999 |
| DOI： |
| KeyWords:rays Low doses Lens Transmission electron microscope Slit lamp microscope |
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| Abstract:: |
| Objective To investigate and evaluate low dose γ-ray radiation induced lens damage. Methods Both eyes of each rabbit were exposed to a single dose of 25 or 50 cGy γ-rays in two groups,respectively. Samples were examined by transmission electron microscopy (TEM) and slit lamp microscopy (SLM)after irradiation. Results Three days after 25 and 50 cGy irradiation,the epithelial cells of lens equatoral region showed marked swelling and many vacuoles formed in intercellular space and cytoplasm,and accompanied by increased multilamellar bodies. Five months after irradiation,SLM of both groups showed that the posterior subcapsule cortex exhibited clusters of vaculoes; 11 months after 50 cGy irradiation,the posterior subcapsule and deep cortex manifested marked cloudy opacities. Conclusion Low doses of γ-ray (25 and 50 cGy) irradiation can markedly damage lens of rabbits. |
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