ZHOU Xiao,WU Dechang,CHENG Shujun.Isolation and cloning of genes related to the transformation of immortalized human bronchial epithelial cell line induced by alpha particle radiation[J].Chinese Journal of Radiological Medicine and Protection,1999,19(3):177-179
Isolation and cloning of genes related to the transformation of immortalized human bronchial epithelial cell line induced by alpha particle radiation
Received:February 24, 1998  Revised:July 14, 1998
DOI:
KeyWords:α-Radiation  Human bronchial epithelial immortalized cell line  mRNA differential display  Genes related to transformation
FundProject:国家自然科学基金;中国博士后科学基金
Author NameAffiliation
ZHOU Xiao 100850 北京放射医学研究所 
WU Dechang 100850 北京放射医学研究所 
CHENG Shujun 中国医学科学院肿瘤研究所病因室 
胡迎春 100850 北京放射医学研究所 
舒为群 中国医学科学院肿瘤研究所病因室 
李刚 100850 北京放射医学研究所 
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Abstract::
      Objective To find out the genes related to transformation of human bronchial epithelial cell line and to clone them. Methods The mRNA differential display method was used. Results Differential cDNA fragments were found.After sequencing and identification in GenBank,4 fragments were found to be novel ones and were registered in EMBL database. Conclusion Four novel cDNA fragments have been found,but their biological characterictics and functions are still to be elucidated.
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