| LIU Linlin,LIU Jianxiang,JU Guizhi.Effect of X rays on mIL-2R expression of human lymphocytes[J].Chinese Journal of Radiological Medicine and Protection,1999,19(1):24-26 |
| Effect of X rays on mIL-2R expression of human lymphocytes |
| Received:September 15, 1998 Revised:December 11, 1998 |
| DOI： |
| KeyWords:Ionizing radiation mIL-2R Adaptive response |
| FundProject:国家自然科学基金 |
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| Abstract:: |
| Objective The mIL-2R expression of human peripheral blood lymphocytes after X irradiation with different doses was investigated.Method Indirect fluorescence analysis with flow cytometry was used. Results After 4 Gy or 6 Gy irradiation,the expression of mIL-2R was significantly lower than that of control (both P <0.01).However,the mIL-2R expression of lymphocytes was significantly higher than that of the control after irradiation with 75 mGy or 100 mGy ( P <0.001 and P <0.01,respectively).Furthermore, it was demonstrated that the mIL-2R expression in the group preirradiated with 75 mGy was higher than that in group irradiated with 4 Gy only. Conclusion 4 Gy or 6 Gy X-irradiation reduced the mIL-2R expession of human peripheral blood lymphocytes,while mIL-2R expression was increased after irradiation with 75 mGy or 100 mGy;75 mGy preirradiation could induce adaptive response of mIL-2R expression. |
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