| CHEN Xinghua,LUO Chengji,GUO Chaohua.Capacity of bone marrow colony forming unit fibroblasts in vitro from mice with combined radiation burn injury[J].Chinese Journal of Radiological Medicine and Protection,1999,19(1):22-23 |
| Capacity of bone marrow colony forming unit fibroblasts in vitro from mice with combined radiation burn injury |
| Received:June 17, 1998 Revised:October 27, 1998 |
| DOI： |
| KeyWords:Radiation injury Burn Combined radiation burn injury Bone marrow Stromal cells Mice |
| FundProject:全军“八五”攻关基金 |
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| Abstract:: |
| Objective To investigate the capacity of bone marrow colony forming unit fibroblasts (CFU F) from mice with combined radiation burn injury. Methods Mice were treated with 5.0 Gy γ-ray radiation alone, 15% total body surface area (TBSA) Ⅲ° burn alone or combined radiation burn.The numbers of CFU-Fs were assayed by Dexter′s method. Results The numbers of CFU-Fs from mice with radiation and combined radiation burn injury were significantly decreased,compared with those of controls and mice with burn injury alone ( P <0.05-0.01). Conclusion The results reveal that the repairing process of bone marrow stromal cells from mice with radiation injury and combined radiation-burn injury is slow,and the combined radiation-burn injury inflicted on the stromal cells possesses the characteristic of radiation injury. |
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