| Wang Zhiquan,Sun Yuanming,Li Jin,et al.Rapid detection of chromosome rearrangement in medical diagnostic X-ray workers by using fluorescence in situ hybridization and study on dose estimation[J].Chinese Journal of Radiological Medicine and Protection,1998,18(4):263-265 |
| Rapid detection of chromosome rearrangement in medical diagnostic X-ray workers by using fluorescence in situ hybridization and study on dose estimation |
| Received:October 31, 1997 Revised:December 22, 1997 |
| DOI： |
| KeyWords:Fluorescence in situ hybridization Medical diagnostic X-ray workers Biological dose |
| FundProject:日中医学会和中国医学科学院中国协和医科大学院校基金 |
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| Abstract:: |
| Objective Biological doses were estimated for medical diagnostic X-ray workers.Methods Chromosome rearrangements in X-ray workers were analysed by fluorescence in situ hybridization (FISH) with composite whole chromosome paintings 4# and 7#.Results The frequency of translocation in medical diagnostic X-ray workers was much higher than that in control group (P<0.01).The biological doses to individual X-ray workers were calculated by their translocation frequency.The translocation frequencies of both FISH and G banding were in good agreement.Conclusion The biological doses to X-ray workers are estimated by FISH first when their dosimetry records are not documented. |
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