Bai Yushu,Huang Qilong,Guan Shurong,et al.A comparative study on micronuclei induced by fast neutrons versus X and 60Co γ rays in human peripheral blood lymphocytes[J].Chinese Journal of Radiological Medicine and Protection,1998,18(4):259-262
A comparative study on micronuclei induced by fast neutrons versus X and 60Co γ rays in human peripheral blood lymphocytes
Received:October 20, 1997  Revised:January 19, 1998
DOI:
KeyWords:Fast neutrons  X-rays  60Co γ rays  Relative biological effectiveness
FundProject:卫生部科学研究基金
Author NameAffiliation
Bai Yushu Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China 
Huang Qilong Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China 
Guan Shurong Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China 
马剑锋 Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China 
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Abstract::
      Objective To compare the effectiveness of 2.14MeV neutrons versus 180kV X-rays and 60Co γ rays in producing micronuclei in human lymphocytes.Methods Heparinized whole blood samples were exposed to fast neutrons, X-rays and 60Co γ rays, respectively.Micronuclei in binuclear lymphocytes(CB method)were scored.Relative biological effectiveness (RBE) values were derived.Results RBE values of 2.14MeV neutrons ranging from 1 to 3 Gy decreased with increasing dose.They averaged 3.88(Dx/Dn) and 4.50(Dγ/Dn), respectively.Conclusion 2.14MeV neutrons have higher biological effectiveness in inducing micronuclei.
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