| Bai Yushu,Huang Qilong,Guan Shurong,et al.A comparative study on micronuclei induced by fast neutrons versus X and 60Co γ rays in human peripheral blood lymphocytes[J].Chinese Journal of Radiological Medicine and Protection,1998,18(4):259-262 |
| A comparative study on micronuclei induced by fast neutrons versus X and 60Co γ rays in human peripheral blood lymphocytes |
| Received:October 20, 1997 Revised:January 19, 1998 |
| DOI： |
| KeyWords:Fast neutrons X-rays 60Co γ rays Relative biological effectiveness |
| FundProject:卫生部科学研究基金 |
| Author Name | Affiliation | | Bai Yushu | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China | | Huang Qilong | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China | | Guan Shurong | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China | | 马剑锋 | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China |
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| Abstract:: |
| Objective To compare the effectiveness of 2.14MeV neutrons versus 180kV X-rays and 60Co γ rays in producing micronuclei in human lymphocytes.Methods Heparinized whole blood samples were exposed to fast neutrons, X-rays and 60Co γ rays, respectively.Micronuclei in binuclear lymphocytes(CB method)were scored.Relative biological effectiveness (RBE) values were derived.Results RBE values of 2.14MeV neutrons ranging from 1 to 3 Gy decreased with increasing dose.They averaged 3.88(Dx/Dn) and 4.50(Dγ/Dn), respectively.Conclusion 2.14MeV neutrons have higher biological effectiveness in inducing micronuclei. |
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