| Lou Bincheng,Ding Xiulan,Zhang Yaochen,et al.Clinical report of eight chief victims in 60Co radiation accident in Xinzhou[J].Chinese Journal of Radiological Medicine and Protection,1998,18(4):225-229 |
| Clinical report of eight chief victims in 60Co radiation accident in Xinzhou |
| Received:November 24, 1997 Revised:February 05, 1998 |
| DOI： |
| KeyWords:Radiation accident Acute radiation sickness GM-CSF |
| FundProject: |
| Author Name | Affiliation | | Lou Bincheng | Department of Emergency Medicine, People's Hospital, Beijing Medical University, Beijing 100044, China | | Ding Xiulan | Department of Emergency Medicine, People's Hospital, Beijing Medical University, Beijing 100044, China | | Zhang Yaochen | Department of Emergency Medicine, People's Hospital, Beijing Medical University, Beijing 100044, China | | 吴红晶 | Department of Emergency Medicine, People's Hospital, Beijing Medical University, Beijing 100044, China | | 郭阳 | Department of Emergency Medicine, People's Hospital, Beijing Medical University, Beijing 100044, China | | 刘秋杰 | Department of Emergency Medicine, People's Hospital, Beijing Medical University, Beijing 100044, China | | 韩伟 | Department of Emergency Medicine, People's Hospital, Beijing Medical University, Beijing 100044, China | | 黄岱坤 | Department of Emergency Medicine, People's Hospital, Beijing Medical University, Beijing 100044, China | | 苗榕生 | Department of Emergency Medicine, People's Hospital, Beijing Medical University, Beijing 100044, China | | 傅冬 | Department of Emergency Medicine, People's Hospital, Beijing Medical University, Beijing 100044, China |
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| Abstract:: |
| Objective This paper presents the clinical diagnosis and treatment of one patient (Fang) with acute radiation sickness(ARS) without obvious history of radiation exposure, the therapeutic effect of simple isolation and administration of GM-CSF and the condition of other seven patients in this group.Methods After collecting detailed history and chromosome aberration analysis of lymphocytes, a definite diagnosis of ARS was made and infectious diseases and poisoning were ruled out.Results When Fang was recovered using GM-CSF and simple isolation, 143 rings plus dicentric aberrations were found in 300 lymphocytes at intermitotic phase, 0.4368 "R+Dic" averagedly exist in every cell, the whole body dose was estimated to be 2.3Gy.Thus, acute radiation sickness of moderate degree was ascertained.It was deduced that 3 other members in Fang's family died of ARS.Altogether about 100 victims were found.Conclusion When a patient suffers suspicious burn(erythema, blistering) but without a history of contact of heat or fire and caustic chemicals and the patient has nausea, vomiting, epilation and decrease in white blood cells, the possibility of radiation exposure exists.If some patients with above manifestations are found in a same family, the radiation exposure may be more probable.A simple isolation ward can be set in an ordinary hospital and GM-CSF should be used to reduce the course. |
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