| Ju Guizhi,Su Xu,Fan Bing,et al.Adaptive response of G1 arrest induced by low dose X-rays[J].Chinese Journal of Radiological Medicine and Protection,1998,18(3):148-150 |
| Adaptive response of G1 arrest induced by low dose X-rays |
| Received:February 28, 1997 Revised:October 20, 1997 |
| DOI： |
| KeyWords:Radiation G1 arrest Adaptive response |
| FundProject:国家自然科学基金 |
| Author Name | Affiliation | | Ju Guizhi | MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences, Changchun 130021, China | | Su Xu | MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences, Changchun 130021, China | | Fan Bing | MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences, Changchun 130021, China | | 刘建香 | MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences, Changchun 130021, China | | 傅士波 | MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences, Changchun 130021, China | | 刘树铮 | MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences, Changchun 130021, China |
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| Abstract:: |
| Objective To investigate whether or not adaptive response of G1 arrest could be induced by low dose radiation.Methods Flow cytometry (FCM) was used to analyze cell cycle stained with propidium iodide (PI).Results It was found that 12h after 1.5 Gy whole body Xirradiation, G1 arrest of thymocytes took place in Kunming mice.However, G1 arrest was diminished when a 0.075 Gy conditioning dose was given 6h before 1.5 Gy challenge dose.The same result was also revealed in EL 4 lymphoma cell line.Conclusion Adaptive response of G1 arrest could be induced by low dose X-rays. |
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