| Zhou Hongning,Wang Qi,Ruan Jianlei.Effects of radiation on transplanted hepatocellular carcinoma in mice[J].Chinese Journal of Radiological Medicine and Protection,1998,18(2):101-103 |
| Effects of radiation on transplanted hepatocellular carcinoma in mice |
| Received:October 03, 1996 Revised:January 13, 1997 |
| DOI： |
| KeyWords:Radiation Transplanted hepatocellular carcinoma |
| FundProject: |
| Author Name | Affiliation | | Zhou Hongning | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China | | Wang Qi | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China | | Ruan Jianlei | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China | | 张翠兰 | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China | | 高凤鸣 | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China | | 李新兰 | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China |
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| Abstract:: |
| Objective The effects of radiation in different doses on transplanted hepatocellular carcinoma in mice were studied.Methods The mice were irradiated with different doses 6 hours before hypodermic injection of H22 hepatocellular carcinoma cells,and the formation and devdlopment of carcinoma in mice were observed,Moreover,the effects of radiation on DTH、NK cell activity and SOD in mice were studied.Results 0.30Gy and 0.60Gy irradiation can delay the formation of carcinoma in mice,0.15Gy and 0.30Gy enhance DTH and NK cell activity in mice and 0.5—1 2Gy raise T SOD and Mn SOD levels in serum.Conclusion The effects of radiation on transplanted hepatocellular carcinoma in mice were relted with that on immune response and SOD level in mice. |
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