.Adaptive response of EL-4 cells on their apoptosis and cell cycle induced by 0.075 Gy X-rays[J].Chinese Journal of Radiological Medicine and Protection,1998,18(2):80-81 |
Adaptive response of EL-4 cells on their apoptosis and cell cycle induced by 0.075 Gy X-rays |
Received:January 14, 1997 Revised:June 02, 1997 |
DOI: |
KeyWords:Radiation EL-4 cells Apoptosis Cell cycle Adaptive response |
FundProject:国家自然科学基金 |
|
Hits: 2285 |
Download times: 1528 |
Abstract:: |
Objective To investigate whether or not adaptive response of EL-4 cells in their apoptosis and cell cycle could be induced by low dose X-rays. Methods Flow cytometry (FCM) was employed. Results It was found that the apoptosis was enhanced by 2 Gy X-rays 12 hour after irradiation accompanied by G0/G1 phase black. However, pre-irradiation with 0.075 Gy X-rays could reduce the level of apoptosis and G0/G1 phase block induced by 2 Gy when the interval between 0.075 Gy and 2 Gy radiation was 6
hours. Conclusion 0.075 Gy pre-exposure could induce adaptive response of apotosis and G1 arrest in EL-4 cells. |
HTML View Full Text View/Add Comment Download reader |
Close |