Jin Cuizhen,Liu Xiulin,Zhang Zeyun.A cytogenetic follow up study of five victims accidentally exposed to 60Co γ-rays[J].Chinese Journal of Radiological Medicine and Protection,1998,18(1):21-25 |
A cytogenetic follow up study of five victims accidentally exposed to 60Co γ-rays |
Received:April 15, 1997 Revised:May 20, 1997 |
DOI: |
KeyWords:Chromosome karyotype analysis Radiation accident Stable type aberrations |
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Abstract:: |
Objective A radiation accident involving a 60Co source occurred in Shanghai in June, 1990 in which five victims were exposed to moderate to high doses (2.0-5.2Gy).Cytogenetic study was extended over 4-6 years after irradiation as one of the major long term follow up surveys to evaluate biological effects of radiation. Method Chromosome slides were prepared using conventional Giemsa stain and G banding method for the karyotype analysis. Results Chromosome analyses revealed that most of remaining aberrations were of stable types and they contributed the major evidence of a dose response relationship. Conclusion These findings provide information that Cs type aberrations are useful for assessing the dose response relationship in those persons who were irradiated many years before cytogenetic examination. |
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