| Tao Zufan,Hiroo Kato,Zha Yongru.Preliminary analysis of data(1987-1990) from investigation of cancer mortality in high background radiation area of Yangjiang, China[J].Chinese Journal of Radiological Medicine and Protection,1997,17(6):376-380 |
| Preliminary analysis of data(1987-1990) from investigation of cancer mortality in high background radiation area of Yangjiang, China |
| Received:June 02, 1997 Revised:July 10, 1997 |
| DOI： |
| KeyWords:High background radiation area Fixed cohort Cancer mortality Relative risk |
| FundProject: |
| Author Name | Affiliation | | Tao Zufan | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China | | Hiroo Kato | 日本 732 广岛, 放射线影响研究所 | | Zha Yongru | 510310 广州, 广东省职业病防治院 | | 秋叶澄伯 | 日本 830, 鹿儿岛, 鹿儿岛大学 | | 孙全富 | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China | | 何伟辉 | 510310 广州, 广东省职业病防治院 | | 林钻轩 | 510310 广州, 广东省职业病防治院 | | 邹剑明 | 510310 广州, 广东省职业病防治院 | | 张守志 | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China | | 刘玉升 | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China | | 菅原努 | 日本 606 京都, 体质研究会 | | 魏履新 | Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China |
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| Abstract:: |
| Objective The cancer mortality study conducted in the high background radiation area (HBRA) of Yangjiang, China, was started in 1972. The major objective of the study was to estimate cancer risk associated with the low level radiation exposure in HBRA. Since 1991, the cancer mortality data were collected from a fixed cohort instead of a dynamic one as in the previous stage. The purpose of the study in the current stage was to accumulate further person-years (Pyr) of observation for improving the statistical power of test in the estimates of cancer risk associated with the natural radiation exposure and to see the reproducibility of the previous results. Methods The collection of cancer mortality data consisted of two phases, the survey of demography and the ascertainment of death causes. The estimates of relative risk (RR) were calculated by AMFIT in Epicure (Hirosoft International Corp., 1988—1992). Results During the period of 1987—1990 there were 231 cancer deaths among 421640 Pyr at risk in the cohort of 106517 subjects, which were classified into four groups based on the hamlet specific average annual gamma ray absorbed doses: three groups (high, medial and low doses) from HBRA and control group from CA. The RRs adjusted for sex and age for each dose group in HBRA compared with the control group for overall cancers and for all cancers except leukemia were less than 1 except for the low dose group, and there seemed to be a trend of RR decrease with the increase of exposure dose from natural radiation, though there was no statistically significant difference. As for the site specific cancer studied, the cancers of lungs, liver, stomach, nasopharnyx and leukemia, the RRs were also less than 1 except for nasopharnyx cancer and for leukemia in the high dose group. The analysis of combined data (1979—1990) showed similar results. Conclusion Although the sample size was not large enough to make definite conclusion statistically, the observation of current follow up period reproduced the previous results obtained from the data up to 1986 that the cancer mortality in HBRA is generally lower than that in CA. Further follow up is necessary. |
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