| Wei Luxin.High background radiation area:an important source of exploring the health effects of low dose ionizing radiation[J].Chinese Journal of Radiological Medicine and Protection,1997,17(6):369-375 |
| High background radiation area:an important source of exploring the health effects of low dose ionizing radiation |
| Received:July 09, 1997 Revised:July 26, 1997 |
| DOI： |
| KeyWords:Radiological epidemiology High background radiation area |
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| Abstract:: |
| Objective For obtaining more effective data from epidemiological investigation in high background radiation areas,it is necessary to analyze the advantages, disadvatages, weak points and problems of this kind of radiation research. Methods For epidemiological investigation of population health effects of high background radiation, the author selected high background radiation areas of Yangjiang (HBRA) and a nearby control area (CA) as an instance for analysis. The investigation included classification of dose groups, comparison of the confounding factors in the incidence of mutation related diseases, cancer mortalities and the frequencies of chromosomal aberrations between HBRA and CA. This research program has become a China Japan cooperative research since 1991. Results The confounding factors above mentioned were comparable between HBRA and CA, and within the dose groups in HBRA, based on a systematic study for many years. The frequencies of chromosomal aberrations increased with the increase of cumulative dose, but not for children around or below 10 years of age. The relative risks (RR) of total and site specific cancer mortalities for HBRA were lower or around 1.00, compared with CA. The incidence of hereditary diseases and congenital deformities in HBRA were in normal range. The results were interpreted preliminarily by the modified “dual radiation action” theory and the “benefit detriment competition” hypothesis. Conclusions The author emphasizes the necessity for continuing epidemiological research in HBRA, especially for international cooperation. He also emphasizes the importance of combination of epidemiology and radiobiology. |
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