| Ao Lin,Cao Jia,Cheng Tianmin,et al.Frequencies of micronucleated polychromatic erythrocytes in mouse bone marrow induced by combined radiation burn injury[J].Chinese Journal of Radiological Medicine and Protection,1997,17(5):309-311 |
| Frequencies of micronucleated polychromatic erythrocytes in mouse bone marrow induced by combined radiation burn injury |
| Received:January 10, 1996 Revised:July 05, 1996 |
| DOI： |
| KeyWords:Micronuclei Combined radiation burn injury Mice Bone marrow |
| FundProject: |
| Author Name | Affiliation | | Ao Lin | Department of Preventive Medicine, The Third Military Medical University, Chongqing 630038, China | | Cao Jia | Department of Preventive Medicine, The Third Military Medical University, Chongqing 630038, China | | Cheng Tianmin | Department of Preventive Medicine, The Third Military Medical University, Chongqing 630038, China | | 杨录军 | Department of Preventive Medicine, The Third Military Medical University, Chongqing 630038, China | | 钱频 | Department of Preventive Medicine, The Third Military Medical University, Chongqing 630038, China | | 刘胜学 | Department of Preventive Medicine, The Third Military Medical University, Chongqing 630038, China |
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| Abstract:: |
| Objective In order to detect if any analysis of frequency of micronucleated polychromatic erythrocytes (fMPCE) in mouse bone marrow was possible to diagnose combined radiation burn injuries. Methods By using the index of fMPCE, the investigation was carried out in the conditions of burn injury alone, radiation injury alone and combined radiation-burn injury. Results The fMPCE induced by 10% and 20% body surface area (BSA) burns were not significantly increased at 24h compared with untreated groups. The fMPCE induced by combined radiation burn injury significantly lower that those by radiation alone, and the fMPCE in the 20% BSA combined radiation-burn injury groups were lower than those in 10% BSA group. Conclusion These results indicate that radiation combined burns have an effect to reduce the fMPCE induced by radiation injury. The reason may be due to the frequency of increase of PCE after burn injury. |
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