An Yan,Cheng Rusong,Xia Xiaobin.Retention pattern of radioiodine in rat thyroid and its dose evaluation[J].Chinese Journal of Radiological Medicine and Protection,1997,17(4):243-247
Retention pattern of radioiodine in rat thyroid and its dose evaluation
Received:February 26, 1996  Revised:June 13, 1996
DOI:
KeyWords:Radioiodine-131  Thyroid  Absorbed dose
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Author NameAffiliation
An Yan China Istitute for Radiation Protection, Taiyuan 030006, China 
Cheng Rusong China Istitute for Radiation Protection, Taiyuan 030006, China 
Xia Xiaobin China Istitute for Radiation Protection, Taiyuan 030006, China 
马如维 China Istitute for Radiation Protection, Taiyuan 030006, China 
郭丰莉 China Istitute for Radiation Protection, Taiyuan 030006, China 
韩月琴 China Istitute for Radiation Protection, Taiyuan 030006, China 
李茂河 China Istitute for Radiation Protection, Taiyuan 030006, China 
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Abstract::
      bjective To study the retention pattern of radioiodine in rat thyroid,observe the biological effect,and assess the harm of radioiodine in human beings. Methods By means of whole body counting,metabolic parameters of radioiodine for the rat thyroid were obtained.The retention equation of iodine in rat thyroid was of a three exponential function. Results By using the three-exponential function,the average accumulated absorbed doses of radioiodine for rat thyroid were estimated to be 7.7Gy and 11.5Gy,respectively.Compared with this method,the ordinary method overestimated the absorbed dose by 66%-91%. Conclusion Considering some factors affecting the dose of radioiodine in rat thyroid after injection,this method can estimate the absorbed dose of radioiodine after injection for rat thyroid of different ages.
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