| Ye Benlan,Cheng Tianmin,Xiao Jiasi.Effects of different components of serum after radiation burn and combined radiation burn injury on inward rectifier potassium channel of myocardial cells[J].Chinese Journal of Radiological Medicine and Protection,1997,17(4):225-229 |
| Effects of different components of serum after radiation burn and combined radiation burn injury on inward rectifier potassium channel of myocardial cells |
| Received:November 15, 1995 Revised:March 18, 1996 |
| DOI： |
| KeyWords:Irradiation Burn Combined radiation burn injury Serum components Myocardial cell Inward rectifier potassium channel |
| FundProject:全军“八五”攻关课题基金 |
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| Abstract:: |
| bjective To study the effects of different components of serum in rats inflicted with radiation, burn and combined radiation-burn injury on inward rectifier potassium channel of cultured myocardial cells. Method Using patch clamp method to study the action of single ion channel. Results The low molecular and lipid components of serum after different injuries models could all activate the inward rectifier potassium channel in cultured myocardial cells. The components of serum after combined radiation burn injury showed the most significant effect, and the way of this effect was different from that from single injury. Conclusion The serum components post injury altered the electric characteristic of myocardial cells, which may play a role in the combined effect of depressed cardiac function after combined radiation burn injury. |
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