Tian Shengli,Cong Xianling.Effects of dsRNA on proliferative reaction and UDS of splenocytes in X-iradiated mice[J].Chinese Journal of Radiological Medicine and Protection,1996,16(4):246-247 |
Effects of dsRNA on proliferative reaction and UDS of splenocytes in X-iradiated mice |
Received:July 19, 1994 Revised:February 27, 1995 |
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KeyWords:dsRNA X-rays UDS proliferative reaction splenocytes |
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Abstract:: |
The effects of different concentratios of dsRNA on proliferative reaction of splenocytes induced by ConA and LPS and on UDS of splenocytes in 1.5Gy X-irradiated mice are reported in this paper.The results showed that the proliferative reaction of splenocytes induced by ConA and LPS in experimental groups increased significantly compared with that in positive group and that UDS in experimental groups was also much enhanced compared with that in positive group when concentration of dsRNA was higher than 6.25mg/kg body weight.It is suggested that dsRNA increases proliferative reaction of splenocytes induced by ConA and LPA and inhibits decrease of UDS induced by X-rays. |
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