Wang Xianli,Su Shijie,Yin Hongshu,et al.Effects of low-dose ionizing radiation on tumor-bearing mice and on radiotherapy[J].Chinese Journal of Radiological Medicine and Protection,1996,16(3):157-160
Effects of low-dose ionizing radiation on tumor-bearing mice and on radiotherapy
Received:March 21, 1995  Revised:July 14, 1995
DOI:
KeyWords:Low-dose ionizing radiation  hormesis  tumor-besring mice  radiotherapy
FundProject:国家自然科学基金
Author NameAffiliation
Wang Xianli 130021 长春, 白求恩医科大学放射医学研究所 
Su Shijie 130021 长春, 白求恩医科大学放射医学研究所 
Yin Hongshu 130021 长春, 白求恩医科大学放射医学研究所 
冯乐平 130021 长春, 白求恩医科大学放射医学研究所 
于开君 白求恩医科大学第三临床学院肿瘤科 
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Abstract::
      We studied the effects of low-dose radiation on tumor-bearing mice and on radiotherapy from hormesis induced by low-dose radiation.The results show that D1 can reduce the tumor rate in mice implanted with tumor cells(P<0.05), and inhibit the tumor growth speed(P<0.05);the effects of radiotherapy on tumor-bearing mice can be enhanced by low-dose radiation.It is further demonstrated that these results are concerned with enhancement of lymphocyte spontaneous proliferation, activity of anti-oxidase, ability of DNA to restore and reduce free radical injury.The above results provide an experimental basis for increasing the efficacy of clinical tumor therapy and alleviating side-effects of radiotherapy.
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