Jiang Benrong.Lymphocyte micronucleus assay can be used as a biological dosimeter in radiation accident[J].Chinese Journal of Radiological Medicine and Protection,1996,16(2):105-108
Lymphocyte micronucleus assay can be used as a biological dosimeter in radiation accident
Received:December 05, 1994  Revised:April 27, 1995
DOI:
KeyWords:Micronuclei  biological dosimeter  calibration curve  cytokinesisblock micronucleus method  radiation accident
FundProject:
Author NameAffiliation
Jiang Benrong Taiping Road Hospital, Beijing, 100039 
姚波 Taiping Road Hospital, Beijing, 100039 
Hits: 3485
Download times: 1906
Abstract::
      We utilized micronucleus (MN) dose-effect calibration curves obtained by cytokinesis-block (CB) method and conventional method to estimate the biological doses to three irradiated persons in a60 Co source accident in Wuhan and one case of nonHodgkin's lymphoma total bodily irradiated with60Co source.The results showed that(1) the doses estimated by micronucleus assay were consistent with those by physical dosimetry and chromosome aberration analysis;(2) the doses estimated 31 days post irradiation were still consistent with those originally estimated to the three accidental cases,although the former were a little lower than the latter.We consider that all of these MNC or MN calibration curves obtained by either CB MN method or conventional MN method could be used as biological dosimeters to estimate the exposure dose in radiation accident.
HTML  View Full Text  View/Add Comment  Download reader
Close

Copyright©    Editorial Office of Chinese Journal of Radiological Medicine and Protection    

Beijing ICP No. 05020547 -2

Address: 2 Xinkang Street, Dewai, Beijing 100088, China

Telephone:010-62389620; Email:cjrmp@cjrmp.sina.net

Technical Support:Beijing E-tiller CO.,LTD.

Visitors:12036026  On-line:0

v
Scan QR Code
&et=44A595A2EC8AD6229C3EE74F9A5C575C190E8AD39916DB990B5B01C235BD8C4870A198C9C8AE435AF87C458A814AE047DE0DC435413F3FA6B70B95DD0CC10648800601D35AF9D4B508EF3C3D74901C5FDDE9F6DD9BDE43CAA57BDA0F24C31D57&pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=D4D466D60FDC1A5A&jid=5E4353813E091AB841B02B880782B82C&yid=8A15F8B0AA0E5323&aid=2CE72A2C6644564A1E72B2B51FB63913&vid=&iid=0B39A22176CE99FB&sid=03F1579EF92A5A32&eid=6270DC1B5693DDAF&fileno=19960213&flag=1&is_more=0"> var my_pcid="A9DB1C13C87CE289EA38239A9433C9DC"; var my_cid="D4D466D60FDC1A5A"; var my_jid="5E4353813E091AB841B02B880782B82C"; var my_yid="8A15F8B0AA0E5323"; var my_aid="2CE72A2C6644564A1E72B2B51FB63913";