| Xu Guizhen,Li Xiuyi,Gong Shouliang.Effects of low dose radiation on function of peritoneal macrophages in mice[J].Chinese Journal of Radiological Medicine and Protection,1996,16(2):93-95 |
| Effects of low dose radiation on function of peritoneal macrophages in mice |
| Received:December 12, 1994 Revised:March 16, 1995 |
| DOI： |
| KeyWords:Irradiation macrophages engulfing digestion. |
| FundProject:国家自然科学基金 |
| Author Name | Affiliation | | Xu Guizhen | Department of Radiation Biology, Norman Bethune University of Medical Sciences, Changchun, 130021 | | Li Xiuyi | Department of Radiation Biology, Norman Bethune University of Medical Sciences, Changchun, 130021 | | Gong Shouliang | Department of Radiation Biology, Norman Bethune University of Medical Sciences, Changchun, 130021 | | 刘淑春 | Department of Radiation Biology, Norman Bethune University of Medical Sciences, Changchun, 130021 | | 刘树铮 | Department of Radiation Biology, Norman Bethune University of Medical Sciences, Changchun, 130021 |
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| Abstract:: |
| This study was undertaken to observe the effects of single whole body irradiation with 0, 0.05,0.075,0.15,2.0 and 4.0 Gy of X-rays on the function of peritoneal macrophages from Kunming mice in engulfing and digestion of chicken red blood cells (CRBC). The results showed that the engulfing functions of macrophages on CRBC 3 and 5 days after irradiation with 0.05 and 0.075 Gy increased obviously,and their digestive function after irradiation with 0.075 Gy was significantly higer than that in 0 Gy group. However,their engulfing and digestive functions decreased after the irradiation with 2 and 4 Gy.These results suggest that low dose radiation can stimulate the function of nonspecific immunity while large dose radiation can inhibit it. |
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