Bai Yunhong,Wang Dewen,Xu Zaihai,et al.Changes of fibronectin and laminin in radiation pulmonary injury of rats[J].Chinese Journal of Radiological Medicine and Protection,1995,15(5):330-333
Changes of fibronectin and laminin in radiation pulmonary injury of rats
Received:August 23, 1994  Revised:March 24, 1995
DOI:
KeyWords:fibronectin  laminin  rats  lungs irradiation
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Author NameAffiliation
Bai Yunhong Institute of Radiation Medicine, Beijing, 100850 
Wang Dewen Institute of Radiation Medicine, Beijing, 100850 
Xu Zaihai 北京微生物流行病研究所 
杨怡 北京仪器中心 
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Abstract::
      The changes of fibronectin (FN)and laminin (LN) in the rat lungs irradiated locally with 30Gy were observed by light microscopy, electronmicroscopy and immunohistochemistry . The results indicated that distribution of FN and LN in the irradiated lungs was random, the content of FN apparently increased in early phase and gradually decreased in late phase, and the content of LN increased all the way in various degrees.The results suggest that FN is mainly related to the generation and development of early pathological changes in radiation pulmonary injury, whereas LN is related to its entire process .
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