Jiang Benrong,Guo Yong,Yao Bo,et al.An approach to possible whole body equivalent dosimetry in case of half body exposure by micronucleus assay[J].Chinese Journal of Radiological Medicine and Protection,1995,15(4):243-247
An approach to possible whole body equivalent dosimetry in case of half body exposure by micronucleus assay
Received:August 23, 1994  Revised:January 04, 1995
DOI:
KeyWords:Micronuclei  anthropomorphous phantom  whole body  exposure dose  equivalent dose
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Author NameAffiliation
Jiang Benrong North Taiping Road Hospital, Beijing, 100039 
Guo Yong North Taiping Road Hospital, Beijing, 100039 
Yao Bo North Taiping Road Hospital, Beijing, 100039 
陈志坚 North Taiping Road Hospital, Beijing, 100039 
郭勇 北京放射医学研究所 
朱云平 北京放射医学研究所 
王兴功 北京放射医学研究所 
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Abstract::
      An approach to the possibility of dosimetry of a corresponding uniform whole body irradiation in case of half body exposures by micronucleus (MN) assay, validated by dosimetry of a nonuniform tissue-equivalent anthropomorphous phantom and clinical manifestations is presented in this paper. The results show that the dose estimated by the frequencies of micronuclei was basically consistent with that of hemopoietic stem cell survival weighted whole body dose measured and calculated with LiF (Mg, Ti) M thermoluminescence detectors distributed in the phantom and with the clinical manifestations.There was no or just a mild decrease in WBC and BPC post irradiation, but the majority of these exposed patients had nausea and vomiting, which were certainly related to the whole abdominal exposures. Hence, we consider that under a condition of half body irradiation,the biological dosimetry with MN assay can be used to indicate the whole body equivalent dose and to reflect the seriousness of the whole body radiation injuries.
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