| Lu Yumin,Fu Baohua,Chen Yuhao,et al.Comparison of chromosome aberration type in lymphocytes and sperm in two cases exposed to accidental radiation[J].Chinese Journal of Radiological Medicine and Protection,1995,15(3):178-181 |
| Comparison of chromosome aberration type in lymphocytes and sperm in two cases exposed to accidental radiation |
| Received:April 20, 1994 Revised:August 05, 1994 |
| DOI： |
| KeyWords:60Co radiation accident human spermatozoa lymphocytes structural chromosome aberrations |
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| Abstract:: |
| The types of structural chromosome abnormalities in human spermatozoa and lymphocytes in two cases exposed to 60Co whole-body six or seven years earlier are analyzed,and the repair mechanism of radiation-induced chromosome lesions are discussed.The frequency of breakage-type is two times higher than that of exchange-type in spermatozoa while the frequency of exchange-type is two times higher than that of breakage-type in lymphocytes.The frequency of chromosome-type aberrations is five times higher than that of chromatid-type aberrations in sperm,and nine times in lymphocytes.The stable,semistable and unstable types account for 14%,46% and 40% of structural abnormalities in spermatozoa,respectively and 29%,52%,19%,in lymphocytes respectively.The results indicate that the types of structural chromosome aberrations in human sperm are different from those in lymphocytes.The repair ability of radiation-induced chromosome lesions in the germ cells at different stages of spermatogenesis and lymphocytes is probably different. |
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