Wang Deqing,Shen Wenmei,Tian Yaping.Protective effect of total flavonoids of astragalus mongholicus Bunge on ONA strand breaks,in V79 cells caused by γ-rays[J].Chinese Journal of Radiological Medicine and Protection,1995,15(2):106-107
Protective effect of total flavonoids of astragalus mongholicus Bunge on ONA strand breaks,in V79 cells caused by γ-rays
Received:May 03, 1994  Revised:August 19, 1994
DOI:
KeyWords:γ-rays  V79 cells  DNA  flavonoids  astragalus mongholicus Bunge  fluorometry
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Author NameAffiliation
Wang Deqing 100853 北京, 解放军总医院生化科 
Shen Wenmei 100853 北京, 解放军总医院生化科 
Tian Yaping 100853 北京, 解放军总医院生化科 
刘国廉 100850 北京, 北京放射医学研究所 
杨素霞 100850 北京, 北京放射医学研究所 
周淑珍 100850 北京, 北京放射医学研究所 
孙仲怡 100850 北京, 北京放射医学研究所 
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Abstract::
      In the report DNA strand breaks in V79 cells caused by γ-rays and the protective effect of total flavonoids of astragalus mongholicus Bunge(TFA)have been studied by fluorometric assay of DNA unwinding.The results indicated that the rate of DNA strand break increased with the increase of γ-ray doses.Even When the concentration of TFA was as low as 0.6/ml,it still showed some protective effect on DNA strand breaks.When its concentration was up to l.2mg/ml,TFA could effectively protect DNA from radiation damage.
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