| Ju Guizhi,Su Xu,Qi Jin.Effect of 15 Gy whole body irradiation with X-rays on expression of CD3 molecules in thymus of mice[J].Chinese Journal of Radiological Medicine and Protection,1995,15(2):93-95 |
| Effect of 15 Gy whole body irradiation with X-rays on expression of CD3 molecules in thymus of mice |
| Received:June 13, 1994 Revised:September 12, 1994 |
| DOI： |
| KeyWords:Whole body irradiation CD3 expression thymocytes |
| FundProject:国家自然科学基金 |
| Author Name | Affiliation | | Ju Guizhi | MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences, Changchun, 130021 | | Su Xu | MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences, Changchun, 130021 | | Qi Jin | MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences, Changchun, 130021 | | 张迎春 | MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences, Changchun, 130021 | | 刘建相 | MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences, Changchun, 130021 | | 刘树铮 | MH Radiobiology Research Unit, Norman Bethune University of Medical Sciences, Changchun, 130021 |
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| Abstract:: |
| The effect of whole body irradiation on CD3 expression of thymocytes was investigated in Kunming mice which were irradiated with 15 Gy X-rays at the dose rate of 0.286 Gy/min.At 18h after irradiation the mice were sacrificed and the changes of CD0+,CD4+,CD8+ cells were measured by flow cytometry with immunofluorescence.The results showed that the CD8cells in the irradiated group increased 177.61 percent over the control group because of the increase of CD4+CD8- and CD4-CD8+ cells with CD3 complex while the CD4+CD8+ cells markedly decreased following irradiation. |
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