| 王猷嘉,韩光.肺癌患者接受放疗和免疫治疗后引发治疗相关性肺炎的研究进展[J].中华放射医学与防护杂志,2024,44(8):711-717.Wang Youjia,Han Guang.Advances in research on treatment-associated pneumonitis in lung cancer patients treated with radiation combined with immunotherapy[J].Chin J Radiol Med Prot,2024,44(8):711-717 |
| 肺癌患者接受放疗和免疫治疗后引发治疗相关性肺炎的研究进展 |
| Advances in research on treatment-associated pneumonitis in lung cancer patients treated with radiation combined with immunotherapy |
| 投稿时间：2024-01-27 |
| DOI：10.3760/cma.j.cn112271-20240127-00034 |
| 中文关键词: 肺癌 放射治疗 免疫检查点抑制剂 放射-免疫相关性肺炎 |
| 英文关键词:Lung cancer Radiotherapy Immune checkpoint inhibitor Radiation-induced immune-related pneumonitis |
| 基金项目:中华国际医学交流基金中青年医学研究专项基金(Z-2014-06-2102);武汉市2022年度知识创新专项(2022020801010512); |
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| 中文摘要: |
| 放射治疗和免疫治疗作为当下癌症治疗的重要组成部分,带来治疗效果的同时也伴随着不良反应的发生。胸部恶性肿瘤患者接受放疗联合免疫治疗后,生存率及生活质量没有达到预期的高度,其中一项主要原因就是治疗相关性肺炎的发生。为了更深入地了解放疗联合免疫治疗肺癌所导致的肺炎,在此对其发病机制、发病情况与危险因素、鉴别诊断与治疗作一综述。 |
| 英文摘要: |
| Radiotherapy and immunotherapy prove significant for cancer treatment presently. Despite therapeutic effects, they carry risks of adverse reactions. The survival rates and quality of life of patients with thoracic malignancies frequently fail to fulfill expectations after they receive radiotherapy combined with immunotherapy. A major reason for this is the occurrence of treatment-associated pneumonitis. To gain a deeper understanding of the pneumonitis induced by radiotherapy combined with immunotherapy for lung cancer, this paper reviews the pathogenesis, incidence, risk factors, differential diagnosis, and treatment of such pneumonitis. |
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