中华放射医学与防护杂志

郁艳军,邓敏敏,高彦祥,王钦,程金生,张富利.国产自主研发二维水箱应用于螺旋断层加速器束流质控的可行性研究[J].中华放射医学与防护杂志,2024,44(4):272-277

国产自主研发二维水箱应用于螺旋断层加速器束流质控的可行性研究

Feasibility of a domestically developed two-dimensional water tank for quality control of beam of a helical TomoTherapy system

投稿时间：2023-05-30

DOI：10.3760/cma.j.cn112271-20230530-00167

中文关键词: 国产二维水箱螺旋断层加速器 γ分析

英文关键词:Domestic 2D water tank Helix Tomotherapy Gamma analysis

基金项目:北京市科技计划(Z181100001718011)

作者	单位	E-mail
郁艳军	中国人民解放军总医院第七医学中心放疗科, 北京100700
邓敏敏	中国人民解放军总医院第七医学中心放疗科, 北京100700
高彦祥	中国人民解放军总医院第七医学中心放疗科, 北京100700
王钦	首都医科大学附属北京世纪坛医院放疗科, 北京100038
程金生	中国疾病预防控制中心辐射防护与核安全医学研究所中国疾病预防控制中心放射防护与核应急重点实验室世界卫生组织辐射与健康合作中心, 北京100088
张富利	中国人民解放军总医院第七医学中心放疗科, 北京100700	radiozfli@163.com

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中文摘要:

目的使用国产二维水箱在螺旋断层加速器(TOMO)上测量百分深度剂量(PDD)和射野离轴剂量分布,探索其应用于TOMO束流质控的可行性。方法使用国产二维水箱在TOMO上采集数据。选择40.0 cm × 1.0 cm、40.0 cm × 2.5 cm、40. 0 cm × 5.0 cm 3个射野测量水下1.5、5.0、10.0、15.0、20.0 cm深度的横向离轴剂量分布,选择25.0 cm × 1.0 cm、25.0 cm × 2.5 cm、25.0 cm × 5.0 cm 3个射野测量百分深度剂量曲线以及水下1.5、5.0、10.0、15.0、20.0 cm 深度的纵向离轴剂量分布,将所有数据导入TEMS软件进行γ分析。结果以厂家金标准数据为基准,国产水箱PDD曲线在3个射野条件下基本吻合,建成区差异偏大,PDD₂₀/PDD₁₀相对偏差>1%。横向离轴剂量分布在3个不同射野条件下除20.0 cm外其他4个深度处所测四分之一高宽(FWQM)均<1%;在3个不同射野、不同深度条件下所测数据在2%/1 mm标准下γ值均>1。纵向离轴剂量分布除射野25.0 cm × 1.0 cm外,其他两个射野不同深度条件下所测半高宽(FWHM)均<1%;除射野25.0 cm × 5.0 cm、深度为15.0和20.0 cm外,其他不同射野不同深度条件下所测数据在2%/1%射野宽度的分析标准下γ值均>1。结论国产二维水箱部分满足TOMO日常质控需求但仍需进一步优化改进以完全满足TOMO的临床验收需求。

英文摘要:

Objective To measure percentage depth dose (PDD) and the off-axis dose profiles of radiation fields using a domestically developed two-dimensional (2D) water tank on a helical TomoTherapy (TOMO) system and to explore the feasibility of the 2D water tank in the application to the beam quality control of the TOMO system. Method The beam data of the TOMO system were collected using the domestically developed 2D water tank. Three radiation fields, 40.0 cm ×1.0 cm, 40.0 cm × 2.5 cm, and 40.0 cm×5.0 cm, were selected to measure the transverse off-axis dose profiles at depths of 1.5, 5.0, 10.0, 15.0 and 20.0 cm. Other three radiation fields, 25.0 cm × 1.0 cm, 25.0 cm ×2.5 cm, and 25.0 cm × 5.0 cm, were employed to determine the PDD curves and longitudinal off-axis dose profiles at depths of 1.5, 5.0, 10.0, 15.0 and 20.0 cm. The gamma analysis of all data was performed using the TomoTherapy ElectroMeter Measurement System (TEMS). Results Compared to the manufacturer's gold standard data, the PDD curves of the domestically developed 2D water tank agreed well under three radiation fields but differed greatly in the build-up regions, with the relative deviation of the PDD₂₀/PDD₁₀ ratio greater than 1%. Under three different radiation fields, the transverse off-axis dose profiles displayed full width at quarter maximum (FWQM) less than 1% measured at four depths except for 20.0 cm. The data measured under three different radiation fields and depths had gamma values greater than 1 based on a gamma criterion of 2%/1 mm. Under different depths and the three radiation fields except for 25.0 cm × 1.0 cm, the longitudinal off-axis dose profiles displayed FWHM less than 1%. Except for radiation field 25.0 cm × 5.0 cm and depths 15.0 and 20.0 cm, the data measured under other different radiation fields and depths had gamma values larger than 1 based on a gamma criterion of 2%/(1% of radiation field width). Conclusions The domestic 2D water tank partially meets the demand for the daily quality control of a TOMO system. Nevertheless, further optimization and improvement are still required to fully meet the requirements of the clinical acceptance of a TOMO system.

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