刘晓宇,郑杰,李库林,尤华彦,李晓燕,党时鹏,赵晓溪,王如兴.心房颤动冷冻球囊消融与磁导航指导下消融放射暴露对比研究[J].中华放射医学与防护杂志,2023,43(7):547-553
心房颤动冷冻球囊消融与磁导航指导下消融放射暴露对比研究
Clinical study of radiation exposure from atrial fibrillation catheter ablation guided by magnetic navigation system and cryoballoon
投稿时间:2022-12-14  
DOI:10.3760/cma.j.cn112271-20221214-00487
中文关键词:  磁导航|冷冻球囊|心房颤动|心血管介入|X射线
英文关键词:Remote magnetic navigation|Cryoballoon|Atrial fibrillation|Cardiovascular intervention|X-rays
基金项目:国家自然科学基金(82000317,81770331)
作者单位E-mail
刘晓宇 南京医科大学附属无锡市人民医院心内科, 无锡 214023  
郑杰 南京医科大学附属无锡市人民医院心内科, 无锡 214023  
李库林 南京医科大学附属无锡市人民医院心内科, 无锡 214023  
尤华彦 南京医科大学附属无锡市人民医院心内科, 无锡 214023  
李晓燕 南京医科大学附属无锡市人民医院心内科, 无锡 214023  
党时鹏 南京医科大学附属无锡市人民医院心内科, 无锡 214023  
赵晓溪 南京医科大学附属无锡市人民医院心内科, 无锡 214023  
王如兴 南京医科大学附属无锡市人民医院心内科, 无锡 214023 ruxingw@aliyun.com 
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中文摘要:
      目的 对比分析心房颤动(房颤)冷冻球囊(CRYO)消融术与磁导航(RMN)指导下房颤消融术两种消融方式,探讨房颤消融术中减少放射暴露的方法。方法 回顾性分析本院144例冷冻消融患者(CRYO组)和121例磁导航指导下房颤消融患者(RMN组)术中在线随机参考点累积皮肤表面入射剂量(CD)和X射线照射时间,分析不同类型患者辐射剂量及手术效果之间的差异。结果 与RMN组相比,CRYO组患者的手术时间明显缩短[(165.0±23.6)、(97.8±18.4)min,t=26.05, P<0.001],但X射线暴露时间明显延长 [(8.1±3.1)、(23.4±6.2)min, t=-24.57,P<0.001]、CD值明显增加[(232.3±130.7)、(669.0±387.5)mGy,Z=-12.29, P<0.001]。随访两组患者总体维持窦性心律比例未见明显差异(71.9%、75.7%,P=0.618)。多元回归分析提示,肥胖患者、非阵发性房颤患者、肺静脉存在变异患者与CRYO组患者CD值增加有关(t=5.47、2.23、3.39,P<0.05),且CRYO组上述3类患者X射线暴露时间也增加(t=2.87、3.86、3.25,P<0.05)。但RMN组中仅有肥胖患者CD值增加(Z=-4.15,P<0.001),且X射线暴露时间不增加。CRYO组和RMN组上述3类患者对比在随访期间维持窦性心律方面未见明显差异(P>0.05)。结论 与RMN房颤消融术相比,CRYO消融术放射暴露明显增加,但手术时间减少,其中肥胖患者、非阵发性房颤患者和肺静脉变异的患者放射暴露量更多,对于这类患者改用RMN消融可在不影响手术效果的同时减少放射暴露。
英文摘要:
      Objective To identify the method to reduce X-ray exposure during ablation of atrial fibrillation (AF) by comparing the cryoballoon (CRYO) ablation and remote magnetic navigation (RMN) ablation. Methods A retrospective analysis was conducted on 144 patients undergoing CRYO ablation (CRYO group) and 121 patients undergoing RMN ablation (RMN group) in our hospital. Entrance surface doses at reference points online, exposure time during procedure and outcomes were analyzed for different types of patients. Results Compared with the RMN group, the procedure time for the CRYO group significantly decreased [(165.0±23.6), (97.8±18.4) min, t=26.05, P<0.001]. However, the entrance surface dose value [(232.3±130.7), (669.0±387.5) mGy, Z=-12.29, P<0.001] and X-ray exposure time [(8.1±3.1), (23.4±6.2) min, t=-24.57, P<0.001] increased significantly for the CRYO group. No significant difference was found between the two groups in the proportion of maintaining sinus rhythm during follow-up of patients (71.9%, 75.7%, P=0.618). Multiple regression analysis showed that obese patients, patients with non-paroxysmal AF and patients with variant pulmonary veins were associated with an increase in entrance surface dose values in the CRYO group (t=5.47, 2.23, 3.39, P<0.05). The X-ray exposure time for the three types patients above in the CRYO group also increased (t=2.87, 3.86, 3.25, P<0.05) in the CRYO group. However, only obese patients in the RMN group had an increase in entrance surface dose value (Z=-4.15, P<0.001) and no increase in exposure time. For the three types of patients above, there was no significant difference in proportion of maintaining sinus rhythm between the CRYO group and the RMN group during follow-up (P>0.05). Conclusions Compared with RMN ablation, the radiation exposure of CRYO AF ablation significantly increased, especially in obese patients, patients with non-paroxysmal AF and patients with pulmonary veins variation. The use of RMN for these types of patients may reduce the radiation exposure without affecting the procedure outcomes.
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