李菲,赵红福.宫颈癌近距离放射治疗阴道不良反应与剂量效应关系[J].中华放射医学与防护杂志,2022,42(12):999-1003
宫颈癌近距离放射治疗阴道不良反应与剂量效应关系
The side effects and dose-effect relationship of vagina in the brachytherapy for cervical cancer
投稿时间:2022-09-13  
DOI:10.3760/cma.j.issn112271-20220913-00371
中文关键词:  宫颈癌|近距离放射治疗|阴道剂量|不良反应
英文关键词:Cervical cancer|Brachytherapy|Vaginal dose|Side effects
基金项目:吉林省科技厅项目(20190303151SF;20210401138YY)
作者单位E-mail
李菲 吉林大学中日联谊医院 放疗科, 长春 130033  
赵红福 吉林大学中日联谊医院 放疗科, 长春 130033 zhaohf@jlu.eud.cn 
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中文摘要:
      近距离放射治疗是宫颈癌根治性放射治疗和术后放射治疗不可替代的重要组成部分。阴道与宫颈相邻的解剖位置关系以及阴道施源器放置于膀胱和直肠之间的阴道内,决定了阴道吸收剂量极度不均匀和难以评估。本文综述了宫颈癌近距离放射治疗中阴道不良反应发生情况、阴道剂量评估方法、剂量不良反应相关性和剂量限值,以期为宫颈癌近距离放射治疗的临床实践提供一定借鉴。
英文摘要:
      Brachytherapy is irreplaceable in definitive radiotherapy and postoperative radiotherapy for cervical cancer. Since the vagina is adjacent to the cervix in terms of anatomical position and the vaginal applicator is placed in the vagina between the bladder and the rectum, the absorbed dose of the vagina is extremely uneven and difficult to evaluate. This review expounds the present vaginal side effects, vaginal dose evaluation method, dose-effect relationship between dose and side effects, and dose limits in brachytherapy for cervical cancer, to provide a certain reference for the clinical practice of the brachytherapy for cervical cancer.
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