| 梁纳,张勇,李荣清.多模态功能成像及影像组学预测直肠癌放化疗疗效研究进展[J].中华放射医学与防护杂志,2022,42(1):73-77.Liang Na,Zhang Yong,Li Rongqing.Progress in predicting the efficacy of neoadjuvant chemoradiation for treating rectal cancer using multimodal functional imaging and radiomics technologies[J].Chin J Radiol Med Prot,2022,42(1):73-77 |
| 多模态功能成像及影像组学预测直肠癌放化疗疗效研究进展 |
| Progress in predicting the efficacy of neoadjuvant chemoradiation for treating rectal cancer using multimodal functional imaging and radiomics technologies |
| 投稿时间：2021-09-18 |
| DOI：10.3760/cma.j.cn112271-20210918-00383 |
| 中文关键词: 直肠癌 影像组学 多模态功能成像 |
| 英文关键词:Rectal cancer Radiomics Multimodal functional imaging |
| 基金项目:云南省高校精准放疗科技创新团队（云教发[2020]102号，K1322113） |
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| 中文摘要: |
| 既往常规影像技术及直肠指检、内窥镜等检查主要基于肿瘤形态学信息对直肠癌新辅助放化疗进行疗效预测，效果欠佳。而弥散加权成像（diffusion-weighted，DWI）、动态对比增强（dynamic contrast-enhanced，DCE）和正电子发射型计算机断层显像（positron emission computed tomography，PET-CT）等功能成像及影像组学技术在形态学信息基础上增加了功能参数，蕴含丰富的肿瘤生物学信息，可在肿瘤组织形态学变化之前反映直肠癌患者新辅助放化疗的疗效。本文就多模态功能成像及影像组学技术在直肠癌新辅助放化疗疗效预测中的研究进展作一综述。 |
| 英文摘要: |
| Conventional imaging techniques, digital rectal examination, and endoscopy previously used to predict the efficacy of neoadjuvant chemoradiation for treating rectal cancer are mainly based on the morphological information of tumors, but their treatment efficacy was not satisfying. In comparison, functional parameters are added into functional imaging and radiomics technologies such as diffusion-weighted imaging (DWI), dynamic contrast-enhanced (DCE-MRI), and positron emission computed tomography (PET-CT) based on the morphological information of tumors. These technologies cover rich biological information of tumors and can reflect the efficacy of neoadjuvant chemoradiotherapy of rectal cancer patients before the morphology of tumors changes. This paper reviews the progress made in predicting the efficacy of neoadjuvant chemoradiation for treating rectal cancer using functional imaging and radiomics technologies. |
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