罗云秀,林少民.放疗诱发第二原发肿瘤[J].中华放射医学与防护杂志,2021,41(7):552-556
放疗诱发第二原发肿瘤
Radiotherapy-induced second primarymalignant neoplasms
投稿时间:2021-02-17  
DOI:10.3760/cma.j.issn.0254-5098.2021.07.015
中文关键词:  辐射诱导  放射治疗  第二原发肿瘤
英文关键词:Radiation-induced  Radiotherapy  Secondprimary malignantneoplasm
基金项目:
作者单位E-mail
罗云秀 海南省肿瘤医院放疗科, 海口 570100  
林少民 海南省肿瘤医院放疗科, 海口 570100 linshaomin1963@163.com 
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中文摘要:
      放射治疗是恶性肿瘤治疗的重要手段之一。放疗与手术、系统治疗联合明显改善了患者预后,部分长期存活患者被诊断为第二原发恶性肿瘤如乳腺癌、食管癌、直肠癌、膀胱癌、肉瘤等。本文主要对放疗诱发第二原发肿瘤的剂量效应关系、潜伏期、影响因素、诊断、治疗、预后等内容进行阐述。
英文摘要:
      Radiotherapy is one of the most important treatments of malignant tumors. However, after the radiotherapy combined with surgery and systemic therapy significantly improved the prognosis of cancer patients,somelong-term survivors after radiation exposure were diagnosed as second primary malignancies such as breast cancer, esophageal cancer, rectal cancer, bladder cancer, and sarcoma. This paper mainly discusses the radiotherapy-induced second primary neoplasms in terms of the dose-effect relationship, incubation period, influencing factors, diagnosis, treatment, and prognosis.
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