| 廖芷芸,吴边,杨坤禹.青少年鼻咽癌治疗现状[J].中华放射医学与防护杂志,2021,41(5):390-395 |
| 青少年鼻咽癌治疗现状 |
| Current treatment of juvenile nasopharyngeal carcinoma |
| 投稿时间：2020-08-20 |
| DOI：10.3760/cma.j.issn.0254-5098.2021.05.013 |
| 中文关键词: 青少年 鼻咽癌 诱导化疗 放射治疗 免疫治疗 |
| 英文关键词:Adolescent Nasopharyngeal carcinoma Induction chemotherapy Radiotherapy Immunotherapy |
| 基金项目:国家自然科学基金（81874222） |
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| 摘要点击次数: 1936 |
| 全文下载次数: 891 |
| 中文摘要: |
| 鼻咽癌（NPC）是一种起源于鼻咽部上皮细胞的恶性肿瘤，是青少年人群头颈部最常见的恶性肿瘤之一。青少年鼻咽癌的治疗通常参照成人治疗指南，但是青少年鼻咽癌有其自身的临床特点。对于处于发育阶段的青少年患者来说，治疗的晚期不良反应也不可忽视。寻找适合青少年的治疗方案具有重要意义。本文对青少年鼻咽癌的流行病学、临床特点、治疗现状和有前景的降低治疗强度的策略作一论述，旨在为今后的治疗研究提供思路。 |
| 英文摘要: |
| Nasopharyngeal carcinoma (NPC) is a cancer arising from the nasopharynx epithelium, and is one of the most frequent head and neck malignancies in adolescents. Treatment strategies for juvenile NPC follow the guidelines established for adult NPC. However, juvenile NPC has its distinct clinical characteristics. For juvenile patients in the developmental stage, the late toxicity of treatment should not be ignored. Therefore, it is important to seek appropriate treatment strategies for juvenile NPC. This review gives an overview of the epidemiology, clinical characteristics and current treatment of juvenile NPC, along with the promising strategies to reduce the intensity of treatment in adolescents. This review aims to provide new insight for improving the treatment of this disease. |
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