| 霍小东,霍彬,曹强,等.数字信息行标共面模板在粒子植入治疗肺癌中的临床价值[J].中华放射医学与防护杂志,2021,41(1):19-25.Huo Xiaodong,Huo Bin,Cao Qiang,et al.Clinical value of digital information coplanar template in seed implantation for the treatment lung cancers[J].Chin J Radiol Med Prot,2021,41(1):19-25 |
| 数字信息行标共面模板在粒子植入治疗肺癌中的临床价值 |
| Clinical value of digital information coplanar template in seed implantation for the treatment lung cancers |
| 投稿时间：2020-05-21 修订日期：2020-05-21 |
| DOI：10.3760/cma.j.issn.0254-5098.2021.01.005 |
| 中文关键词: 行标共面模板 通用模板 放射性粒子 治疗计划系统 非小细胞肺癌 |
| 英文关键词:Line mark template General template Radioactive seed Treatment planning system Non-small cell lung cancer |
| 基金项目:天津市教委科研计划项目（自然科学）（2018KJ073）；天津市自然科学基金项目青年项目（18JCQNJC13100） |
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| 中文摘要: |
| 目的 探讨数字信息行标共面模板（以下简称行标模板）在125I放射性粒子植入治疗肺癌中的价值。方法 回顾性分析2017年8月至2019年5月天津医科大学第二医院肿瘤科58例应用模板粒子植入，其中30例应用行标模板，28例应用通用制式共面模板（以下简称通用模板）。比较手术前后90%靶体积的最小吸收剂量（D90）、匹配周边剂量（MPD）及100%、150%、200%处方剂量覆盖的靶区体积占靶区总体积的百分比（分别为V100、V150、V200），靶区外体积指数（EI）、适形指数（CI）和均匀性指数（HI），并比较两组患者手术操作时间的差异。结果 行标组术前计划与术后验证D90、MPD、V100、V150、V200差异无统计学意义（P>0.05）。通用组术前计划与术后验证D90、MPD、V100、V150、V200差异无统计学意义（P>0.05）。行标组和通用组手术时间分别为（44.3±12.4）和（60.0±12.8）min（t=-3.03，P<0.05）。结论 使用模板辅助粒子植入可以精确地达到术前规划，行标模板缩短了手术操作时间，提高了患者的耐受度。 |
| 英文摘要: |
| Objective To explore the value of digital information line mark coplanar template (also referred to as the line mark template) in 125I radioactive seed implantation for the treatment of lung cancers.Methods A retrospective analysis was conducted for 58 cases of lung cancers who were treated with template-assisted seed implantation in Oncology Department of the Second Hospital of Tianjin Medical University from Aug 2017 to May 2019.Line mark templates were adopted for 30 cases (the line mark template group) and general standard coplanar templates (also referred to as the general template) were used for 28 cases (the general template group). Pre-plan and post-implant parameters were compared, including the minimum prescription dose delivered to 90% of target volume (D90), minimum peripheral dose (MPD), mean percentages of volume receiving 100%, 150% and 200% of the prescription doses (V100, V150 and V200), external index (EI), conformity index (CI), and homogeneity index (HI) of target volume.The operation duration was also compared between the two groups.Results There was no statistical difference between pre-plan and post-implant D90, MPD, V100, V150 and V200 in the line mark template group (P>0.05). There was also no statistical difference between pre-plan and post-implant D90, MPD, V100, V150 and V200 of the general template group (P>0.05). The operation duration of the line mark template group and the general template group was (44.3±12.4) and (60.0±12.8) min, respectively (t=-3.03, P<0.05). Conclusions The use of template-assisted seed implantation can accurately achieve preoperative planning, while the line mark template shortens the operation duration and thus improves the tolerance of patients. |
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