| 邹作伟,耿建华,郑容,曹仲年.99Tcm-亚甲基二膦酸盐SPECT骨显像患者的周围辐射水平及其影响因素[J].中华放射医学与防护杂志,2019,39(8):629-634 |
| 99Tcm-亚甲基二膦酸盐SPECT骨显像患者的周围辐射水平及其影响因素 |
| Radiation level in the surroundings of patients undergoing 99Tcm-MDP SPECT bone imaging and influence factors |
| 投稿时间：2019-03-12 |
| DOI：10.3760/cma.j.issn.0254-5098.2019.08.013 |
| 中文关键词: 99Tcm-亚甲基二膦酸盐 骨显像 辐射水平 |
| 英文关键词:99Tcm-MDP Bone imaging Radiation level |
| 基金项目:中国癌症基金会北京希望马拉松专项基金（LC2016A02，LC2018B01） |
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| 中文摘要: |
| 目的 对99Tcm-亚甲基二膦酸盐（MDP）单光子发射计算机断层成像术（SPECT）骨显像患者周围辐射水平及其影响因素进行研究，为保证周围人员辐射安全提供实验依据。方法 对367例中国医学科学院肿瘤医院全身骨显像的患者进行测量，测量其不同时间及不同距离处的周围剂量当量率，分析周围剂量当量率随时间及距离的变化规律，估算周围不同距离处的剂量水平，评估周围人员的辐射剂量。结果 患者周围剂量当量率随时间指数衰减，患者体内99Tcm有效半衰期随时间增加；周围剂量当量率距患者4 m内随距离的变化呈幂函数，平均幂值为-1.45。从患者注射99Tcm药物至患者体内99Tcm基本消失，在距患者0.5、1.0和1.5 m处的周围辐射剂量水平分别为238.3、99.7和61.8 μSv；在注射后不同的时间点（0、3和6 h），与患者距0.5 m滞留10 min，辐射剂量分别为9.9、3.0和1.9 μSv。结论 骨显像患者周围剂量当量率随时间和距离快速降低。骨显像患者会对周围人员造成一定的照射，但是剂量水平远低于国家标准的规定。建议患者进行骨显像的当天尽量不要进行和医护人员长时间近距离接触的其他诊疗。 |
| 英文摘要: |
| Objective To study the radiation level in the surrounding of patients undergoing 99Tcm-MDP SPECT bone imaging and associated influencing factors and provide experimental data for the radiation safety of personnel around the patients. Methods A total of 367 patients undergoing whole-body bone imaging in Cancer Hospital, Chinese Academy of Medical Sciences were investigated to measure the ambient dose equivalent rate around the patients at different time and different distances from the patients, analyze the variations of ambient dose equivalent rate with time and distances, estimate the dose level at different distances around the patients, and evaluate the radiation dose to personnel around the patients. Results The ambient dose equivalent rate around the patient decreased exponentially with time; the effective half-life of 99Tcm in patients' body increased with time. The ambient dose equivalent rate varied by power function with increasing distance within 4 meters from the patient with the mean power value of -1.45. The radiation levels were 238.3 μSv at 0.5 m, 99.7 μSv at 1 m, and 61.8 μSv at 1.5 m from the patient undergoing 99Tcm injection to its vanishing in patients' body. At different time points, the radiation doses at 0.5 m off the patient for 10 min were:9.9, 3.0, 1.9 μSv at 0, 3 and 6 h, respectively. Conclusions The ambient dose equivalent rate around the patients undergoing 99Tcm-MDP SPECT bone imaging decrease rapidly with increasing time and distance. The patients can cause a certain degree of exposures to the surrounding personnel, but the exposure level is far lower than the relevant national standards. It is suggested that the patients should not receive other types of diagnosis and treatments spending lot of time and in close contact with medical staff while bone imaging being conducted on the same day. |
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