| 杜乙,王若曦,岳海振,等.用于精确放疗三维剂量验证的胶体剂量计研究进展[J].中华放射医学与防护杂志,2019,39(7):544-548.Du Yi,Wang Ruoxi,Yue Haizhen,et al.State of the art of gel dosimeters for three-dimensional radiotherapy dose verification[J].Chin J Radiol Med Prot,2019,39(7):544-548 |
| 用于精确放疗三维剂量验证的胶体剂量计研究进展 |
| State of the art of gel dosimeters for three-dimensional radiotherapy dose verification |
| 投稿时间：2018-11-19 |
| DOI：10.3760/cma.j.issn.0254-5098.2019.07.012 |
| 中文关键词: 精确放疗 三维剂量验证 胶体剂量计 |
| 英文关键词:Precision radiotherapy 3D dose verification Gel dosimeters |
| 基金项目:北京市自然科学基金（1184014，1174016）；中国博士后科学基金（2017M620542）；首都卫生发展科研专项（2018-4-1027）；国家自然科学基金（11505012） |
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| 中文摘要: |
| 剂量验证作为放疗质量控制的重要环节，是保证患者安全与治疗效果的重要手段。随着精确放疗技术不断涌现与临床应用，三维剂量验证需求日益突显。胶体剂量计，具有三维剂量测量的固有优势，兼具分辨率高、组织等效性好的特点，是现有临床剂量工具的有效补充。本文对胶体剂量计的工作原理、剂量响应机制、典型剂量计特性与研究进展进行了梳理与综述。胶体剂量计优势突出、应用前景广阔，目前尚有一系列科学问题有待探讨，具有较大科研价值。 |
| 英文摘要: |
| Dose verification, as part of the radiotherapy QA chain, is a significant method to ensure the patients' safety and efficacy of treatment. The increasing application of precision radiotherapy techniques in clinic has advanced the need of three-dimensional (3D) dose verification. Gel dosimeters, prevailing for its intrinsic 3D high-resolution measurement and good tissue equivalence, can serve as effective supplement to the clinical radiotherapy dosimetric system. This paper reviews the method ology, dose response mechanism, characterizations of the state-of-the-art gel dosimeters. Gel dosimeters, outstanding for 3D dose measurement, have a great potential to explore both for clinical application and academic research. |
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