| 高宇,王平,韩林,吕玉民.放射工作人员染色体畸变研究现状[J].中华放射医学与防护杂志,2018,38(8):635-640 |
| 放射工作人员染色体畸变研究现状 |
| The current research status on chromosomal aberrations of radiation workers |
| 投稿时间：2017-12-28 |
| DOI：10.3760/cma.j.issn.0254-5098.2018.08.015 |
| 中文关键词: 低剂量电离辐射 放射工作人员 染色体畸变 |
| 英文关键词:Low-dose ionizing radiation Radiation workers Chromosomal aberrations |
| 基金项目:河南省重点科技公关项目（142102310086）；国家重点临床专科建设项目（2011-17） |
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| 中文摘要: |
| 长期暴露于低剂量电离辐射会对放射工作人员的辐射敏感组织器官造成损伤。目前，常用于评价慢性低剂量电离辐射所致辐射损伤的主要细胞遗传学指标是外周血淋巴细胞染色体畸变。本文对国内外放射工作人员暴露于低剂量电离辐射所致细胞遗传学效应的调查和研究进行综述，了解目前放射工作人员外周血淋巴细胞染色体畸变检测的现状及存在的问题，为国内开展放射工作人员染色体畸变检测与评价提供参考。 |
| 英文摘要: |
| Long-term exposure to low dose ionizing radiation contributes to the damage of radiosensitive tissue and organ in radiation workers. The main cytogenetic index used to evaluate radiation damage induced by chronic low dose ionizing radiation is the chromosome aberrations of peripheral blood lymphocytes. In this paper, the cytogenetic evaluation indicators of radiation workers exposed to low dose ionizing radiation were reviewed basing on the research achievements of domestic and foreign scholars. The goals of this review were to supply the present situation and limitation of chromosomal aberration analysis in peripheral blood lymphocytes of radiation workers and to provide a reference for the chromosomal aberration test and assessment of radiation workers in China. |
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