| 蒋晨雪,顾飞英,许亚萍.c-Met与食管癌放疗敏感性的相关性研究进展[J].中华放射医学与防护杂志,2017,37(12):962-964 |
| c-Met与食管癌放疗敏感性的相关性研究进展 |
| Research progress on the association between c-Met and radiosensitivity in esophageal cancer |
| 投稿时间：2017-05-11 |
| DOI：10.3760/cma.j.issn.0254-5098.2017.12.016 |
| 中文关键词: 食管癌 c-Met 放射敏感性 靶向治疗 |
| 英文关键词:Esophageal cancer c-Met Radiosensitivity Target therapy |
| 基金项目: |
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| 中文摘要: |
| 食管癌是我国常见的消化道肿瘤，预后差。放疗是食管癌的主要治疗方式，肿瘤的放射敏感性是影响放疗疗效的一个重要原因。肝细胞生长因子受体c-Met及其信号通路在肿瘤发生、发展、侵袭、转移以及治疗抵抗等过程中具有重要作用。本文就c-Met与食管癌放疗敏感性的相关性研究进展进行了综述。 |
| 英文摘要: |
| Esophageal cancer is a common gastrointestinal cancer in China with poor prognosis. Radiotherapy is the main treatment of esophageal cancer, and radiosensitivity of the tumor cell is a significant reason for the efficacy of radiotherapy. Mesenchymal-epithelial transition factor (c-Met) and its signaling pathway play an significant role in tumorigenesis, development, invasion, metastasis and treatment resistance. This review summarizes the association between expression of c-Met and radiosensitivity in esophageal cancer. |
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