中华放射医学与防护杂志

董百强,陈明.立体定向放疗在非小细胞肺癌治疗中的应用[J].中华放射医学与防护杂志,2016,36(10):732-735.Dong Baiqiang,Chen Ming.The application of stereotactic body radiotherapy in treatment of non-small cell lung cancer[J].Chin J Radiol Med Prot,2016,36(10):732-735

立体定向放疗在非小细胞肺癌治疗中的应用

The application of stereotactic body radiotherapy in treatment of non-small cell lung cancer

投稿时间：2016-07-12

DOI：10.3760/cma.j.issn.0254-5098.2016.10.003

中文关键词: 立体定向放射治疗非小细胞肺癌不良反应

英文关键词:Stereotactic body radiotherapy Non-small cell lung cancer Side-effects

基金项目:

作者	单位	E-mail
董百强	310022 杭州, 浙江省肿瘤医院放疗科浙江省放射肿瘤重点实验室
陈明	310022 杭州, 浙江省肿瘤医院放疗科浙江省放射肿瘤重点实验室	chenming@zjcc.org.cn

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中文摘要:

体部立体定向放疗（stereotactic body radiation therapy，SBRT）是指应用单次或少数多次给予靶区高剂量照射的治疗方式。和常规放疗相比，具有分割剂量大、精度高等特点。其在肺部肿瘤中的应用可归纳为以下3点：①对于因高龄或合并严重心肺等内科疾病不能手术或不愿接受手术的早期（T_1-2N₀M₀）非小细胞肺癌（non-small cell lung cancer，NSCLC），SBRT已确立标准治疗的地位。②对于可手术的早期NSCLC，SBRT初步应用的结果并不逊于手术。③对于肺内孤立转移灶（1~3个），在全身治疗的基础上给与SBRT已逐步被接受。本文对此作一综述。

英文摘要:

Stereotactic body radiotherapy (SBRT) is a treatment of high dose radiation in a single or small number fractions to the target areas. Compared with conventional radiotherapy, SBRT has the features of higher dose and better precision. The application in lung cancer can be summarized as the following three points:① SBRT has established the status of standard treatment for early (T_1-2N₀M₀) non-small cell lung cancer (NSCLC) patients who unable or unwilling to undergo surgery. ② The results of preliminary application of SBRT in the operable NSCLC are not inferior to surgery. ③ As for isolated metastases (1-3), the combination of systemic treatment and SBRT has been gradually accepted. This article makes a summary of this.

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