| 程德琪,杨沁,黄旭帆,等.基于Geant4的9 MeV电子线FLASH治疗室的辐射场分布研究[J].中华放射医学与防护杂志,2025,45(11):1152-1156.Cheng Deqi,Yang Qin,Huang Xufan,et al.A Geant4-based research on radiation field distribution in a 9 MeV e-FLASH treatment room[J].Chin J Radiol Med Prot,2025,45(11):1152-1156 |
| 基于Geant4的9 MeV电子线FLASH治疗室的辐射场分布研究 |
| A Geant4-based research on radiation field distribution in a 9 MeV e-FLASH treatment room |
| 投稿时间：2025-07-21 |
| DOI：10.3760/cma.j.cn112271-20250721-00259 |
| 中文关键词: 电子线FLASH 辐射水平 Geant4 辐射防护 |
| 英文关键词:e-FLASH Radiation level Geant4 Radiation protection |
| 基金项目: |
| 作者 | 单位 | E-mail | | 程德琪 | 中玖闪光医疗科技有限公司, 绵阳 621000 | | | 杨沁 | 中玖闪光医疗科技有限公司, 绵阳 621000 | | | 黄旭帆 | 中玖闪光医疗科技有限公司, 绵阳 621000 | | | 吴鹏 | 中玖闪光医疗科技有限公司, 绵阳 621000 | | | 谢浩然 | 中玖闪光医疗科技有限公司, 绵阳 621000 | | | 夏静 | 中玖闪光医疗科技有限公司, 绵阳 621000 | | | 汪二峰 | 中玖闪光医疗科技有限公司, 绵阳 621000 | | | 于国福 | 中玖闪光医疗科技有限公司, 绵阳 621000 | | | 蒋雨 | 中玖闪光医疗科技有限公司, 绵阳 621000 | | | 刘贤洪 | 中玖闪光医疗科技有限公司, 绵阳 621000 | xianhong.liu@changhong.com |
|
| 摘要点击次数: 627 |
| 全文下载次数: 286 |
| 中文摘要: |
| 目的 研究9 MeV电子线FLASH(e-FLASH)直线加速器治疗室的辐射场分布特征。方法 采用Geant4蒙特卡罗程序对e-FLASH直线加速器治疗室进行物理建模, 模拟参考点单次出束总剂量50 Gy、剂量率250 Gy/s工况下治疗室内外辐射场分布, 并用高灵敏度辐射检测仪(AT1123)对关注点的实测数据进行验证。结果 参考点处的剂量率约为9×1011 μSv/h, 由于散射和屏蔽的影响, 衰减速率与平方反比定律存在偏差, 等剂量线存在一定漂移。关注点实测剂量率与蒙特卡罗模拟结果吻合良好, 最大偏差在30%以内。结论 Geant4有效模拟e-FLASH治疗室的复杂辐射场分布, 表明Geant4可用于e-FLASH放射治疗场所的屏蔽计算, 为设计优化减少试错, 降低工程成本。 |
| 英文摘要: |
| Objective To investigate the radiation field distribution characteristics in a 9 MeV electron FLASH (e-FLASH) linear accelerator treatment room. Methods The Geant4 Monte Carlo program was employed for physical simulating of the radiation field distribution inside and outside the treatment room under a single-beam delivery condition with a total dose of 50 Gy at the reference point and a dose rate of 250 Gy/s. High-sensitivity radiation detectors (AT1123) were used to validate the measurements at key points. Results The dose rate at the reference point was approximately 9×1011 μSv/h. Due to the scattering and shielding effects, the deviation of the attenuation rate from the inverse-square law was observed and the isodose lines exhibited spatial drift. Measured dose rates at key points showed good agreement with the simulation result, with a maximum deviation within 30%. Conclusions The complex radiation field distribution can be effectively simulated using Geant4 in an e-FLASH treatment room. This indicated the Geant4 is not only applicable for the shielding calculations in e-FLASH radiotherapy facilities, but also for the design optimization through, reduction of trial-and-error iterations and engineering costs. |
| HTML 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|