宣志强,郝小吉,俞顺飞,等.浙江省碘治疗工作人员甲状腺131I内照射水平及剂量估算[J].中华放射医学与防护杂志,2025,45(6):531-536.Xuan Zhiqiang,Hao Xiaoji,Yu Shunfei,et al.Estimation of 131I internal exposure of thyroid and dose to nuclear medicine staff in Zhejiang province[J].Chin J Radiol Med Prot,2025,45(6):531-536
浙江省碘治疗工作人员甲状腺131I内照射水平及剂量估算
Estimation of 131I internal exposure of thyroid and dose to nuclear medicine staff in Zhejiang province
投稿时间:2024-05-09  
DOI:10.3760/cma.j.cn112271-20240509-00171
中文关键词:  核医学  131I  甲状腺  内照射
英文关键词:Nuclear medicine  131I  Thyroid  Internal exposure
基金项目:浙江省医药卫生科学研究基金项目(2022KY133)
作者单位
宣志强 浙江省疾病预防控制中心, 杭州 310051 
郝小吉 浙江省疾病预防控制中心, 杭州 310051 
俞顺飞 浙江省疾病预防控制中心, 杭州 310051 
赖忠俊 浙江省疾病预防控制中心, 杭州 310051 
郭佳娣 浙江省疾病预防控制中心, 杭州 310051 
曹艺耀 浙江省疾病预防控制中心, 杭州 310051 
王东航 浙江省疾病预防控制中心, 杭州 310051 
胡桂佳 浙江省疾病预防控制中心, 杭州 310051 
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中文摘要:
      目的 调查浙江省核医学开展情况,掌握核医学放射工作人员数量,对辖区内从事131I治疗的放射工作人员开展内照射监测与剂量估算。方法 采取普查方法,选取浙江省所有开展131I甲状腺癌治疗的22家医院,采用直接测量法对131I治疗场所的96名工作人员甲状腺131I活度进行测量,并进行内照射有效剂量估算和影响因素分析。结果 22家医院中有19家医院的49名碘治疗工作人员甲状腺131I活度高于仪器探测限,占全部监测对象51.04%,检出活度最高达629.18 Bq。不同岗位、不同性别和不同等级医院的131I治疗工作人员甲状腺131I检出率之间比较差异均无统计学意义(P>0.05)。不同岗位开展131I治疗甲状腺癌工作人员甲状腺131I活度比较,护士岗位最高,其次为技师和医师,最低为保洁人员(H=6.39,P<0.05)。49名检出人员估算的待积有效剂量范围为0.05~2.37 mSv,待积有效剂量<1 mSv的占93.88%。logistic回归分析显示,护士岗位为待积有效剂量的危险因素(OR=2.805,95%CI 1.076~7.314)。结论 浙江省开展碘治疗甲状腺癌工作人员甲状腺131I内照射待积有效剂量未超出剂量限值,但开展碘治疗的工作人员仍需加强内照射防护,采取科学有效防护措施降低工作人员内照射健康危害风险。
英文摘要:
      Objective To investigate the current situation of nuclear medicine practices, determine the number of nuclear medicine staff, conduct internal exposure monitoring and dose estimation for nuclear mecidine staff engaged in 131I treatment in Zhejiang province. Methods A survey was conducted over all the 22 hospitals involved in 131I treatment in the province. The 131I activity in thyroid of 96 stafff in 131I treatment workplaces were measured by means of direct method. At the same time, the effective doses from internal exposure were estimated and the influencing factors were analyzed. Results 131I activity in thyroids was found to be above the detection limit for 49 staff (51.04%) in nineteen hospitals. The maximum value of 131I activity was 629.18 Bq. There was no statistically significant difference in 131I detection rate in thyroid of 131I treatment staff between different positions, different genders and different levels of hospitals (P>0.05). Comparisons of 131I activity of thyroid of nuclear medicine staff for theatment of thyroid cancers had shown that the highest was for nurses, followed by technicians and doctors, and the lowest was for cleaning staff (H=6.39, P<0.05). The estimated committed effective dose to the nuclear medicine staff ranged from 0.05 to 2.37 mSv, with those below 1 mSv accounting for 93.88% of the total. Logistic regression analysis showed that nursing position was the risk factor contributing to the committed effective dose (OR=2.805, 95%CI 1.076-7.314). Conclusions In Zhejiang province, the committed effective dose to thyroid of nuclear medicine staff from 131I internal exposure was not in excess of the dose limit. However, the staff performing iodine therapy still need to strengthen protection against internal exposure and take scientific and effective protective measures to reduce the risk of health hazards from internal exposure.
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