中华放射医学与防护杂志

苗晓翔,苏垠平,武云云,等.我国室内氡致肺癌的疾病负担估算[J].中华放射医学与防护杂志,2024,44(12):1069-1076.Miao Xiaoxiang,Su Yinping,Wu Yunyun,et al.Estimation and evaluation of disease burden of indoor radon-induced lung cancer in China[J].Chin J Radiol Med Prot,2024,44(12):1069-1076

我国室内氡致肺癌的疾病负担估算

Estimation and evaluation of disease burden of indoor radon-induced lung cancer in China

投稿时间：2024-09-24

DOI：10.3760/cma.j.cn112271-20240924-00374

中文关键词: 室内氡氡致肺癌疾病负担估算政策措施

英文关键词:Indoor radon Lung cancer Disease burden Estimation Policies and measures

基金项目:

作者	单位	E-mail
苗晓翔	中国疾病预防控制中心辐射防护与核安全医学所辐射防护与核应急中国疾病预防控制中心重点实验室, 北京 100088
苏垠平	中国疾病预防控制中心辐射防护与核安全医学所辐射防护与核应急中国疾病预防控制中心重点实验室, 北京 100088
武云云	中国疾病预防控制中心辐射防护与核安全医学所辐射防护与核应急中国疾病预防控制中心重点实验室, 北京 100088
王晨冉	国家癌症中心癌症早诊早治办公室中国医学科学院肿瘤医院, 北京 100021
卓维海	复旦大学放射医学研究所, 上海 200032
孙全富	中国疾病预防控制中心辐射防护与核安全医学所辐射防护与核应急中国疾病预防控制中心重点实验室, 北京 100088	sunquanfu@nirp.chinacdc.cn

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中文摘要:

目的估算我国室内氡暴露导致的居民肺癌疾病负担水平,为完善防氡控氡政策措施提供科学依据。方法基于我国室内氡浓度监测调查数据和室内氡致肺癌风险归因研究结果,以及人口、吸烟等基础数据,利用归因疾病负担计算方法,估算我国室内氡致肺癌的疾病负担。结果估计2018年我国室内氡暴露致全人群肺癌的早死寿命损失年(YLL)为510.93万人年,伤残健康寿命损失年(YLD)为5.26万人年,伤残调整寿命年(DALY)为516.19万人年。50~54岁年龄组人群的DALY最高。吸烟男性的室内氡致肺癌归因疾病负担超过吸烟女性的9倍,不吸烟女性的肺癌归因疾病负担超过不吸烟男性的5倍,吸烟与室内氡致肺癌的疾病负担关系密切。结论我国室内氡暴露是与肺癌疾病负担相关的主要环境危险因素,室内氡的健康危害亟需引起更多关注并完善相应政策措施来应对这一挑战。

英文摘要:

Objective To estimate the lung cancer disease burden of residents caused by indoor radon exposure in living rooms in China, and to provide scientific basis for improving radon prevention and control policies and measures. Methods Based on the data from the national indoor radon monitoring survey, the study of lung cancer caused by indoor radon, and the basic data such as population and smoking, the attributable burden of disease calculation method was used to estimate the disease burden of lung cancer caused by indoor radon in China. Results In 2018, it was estimated that the years of life lost due to premature death (YLL), years of life lost due to health disability (YLD) and disability-adjusted life years (DALY) due to indoor radon exposure were 5.109 3 million, 0.052 6 million and 5.161 9 million, respectively. DALY was highest in the 50-54 age group. The disease burden of indoor radon-induced lung cancer in smoking men was more than 9 times that of smoking women, and the disease burden of lung cancer in non-smoking women was more than 5 times that of non-smoking men. Smoking is closely related to the disease burden of indoor radon-induced lung cancer. Conclusions Indoor radon exposure is a major environmental risk factor associated with lung cancer burden in China. The health hazards of indoor radon require more attention and improved policy measures to address this challenge.

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