梁晓雪,高剑波,李睿,等.双层探测器光谱CT低对比剂量肺动脉成像中肺动脉管径对图像质量的影响[J].中华放射医学与防护杂志,2023,43(10):812-819.Liang Xiaoxue,Gao Jianbo,Li Rui,et al.The influence of pulmonary artery diameter on the image quality of dual-layer spectral detector CT pulmonary angiography with low contrast agent dosage[J].Chin J Radiol Med Prot,2023,43(10):812-819
双层探测器光谱CT低对比剂量肺动脉成像中肺动脉管径对图像质量的影响
The influence of pulmonary artery diameter on the image quality of dual-layer spectral detector CT pulmonary angiography with low contrast agent dosage
投稿时间:2023-05-25  
DOI:10.3760/cma.j.cn112271-20230525-00160
中文关键词:  光谱CT  肺动脉成像  肺动脉高压  对比剂
英文关键词:Spectral CT  Pulmonary angiography  Pulmonary hypertension  Contrast agent
基金项目:河南省科技攻关项目(232102310282)
作者单位E-mail
梁晓雪 郑州大学第一附属医院放射科, 郑州 450000  
高剑波 郑州大学第一附属医院放射科, 郑州 450000 cjr.gaojianbo@vip.163.com 
李睿 郑州大学第一附属医院放射科, 郑州 450000  
王小鹏 郑州大学第一附属医院放射科, 郑州 450000  
苏蕾 郑州大学第一附属医院放射科, 郑州 450000  
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中文摘要:
      目的 评价利用低剂量对比剂的双层探测器光谱CT肺动脉成像图像质量,探讨肺动脉管径对图像的影响。方法 回顾性分析2022年3月至8月在郑州大学第一附属医院行双层探测器光谱CT肺动脉成像的91名被检者的影像资料,其中,肺动脉主干直径≥30 mm的34例为组1,肺动脉主干直径<30 mm的57例为组2。对比剂用量为30 ml。两组肺动脉主干至亚段肺动脉的CT值、标准差(SD)、信噪比(SNR)以及对比噪声比(CNR)进行了比较。记录辐射剂量参数CT容积剂量指数(CTDIvol)和有效剂量长度乘积(DLP)。2名阅片者采用3分法评估图像质量,利用Kappa检验分析结果的一致性。结果 两组图像肺动脉主干、左肺动脉干CT值差异无统计学意义(P>0.05)。组1的左肺上叶动脉、段动脉、亚段动脉CT值低于组2(t=-2.13、 -2.17,Z=-2.33,P<0.05)。组1的肺动脉主干和段动脉SD值高于组2(t=2.27, Z=-2.23,P<0.05)。 左肺动脉干、左肺上叶动脉、亚段动脉SD值两组之间差异无统计学意义(P>0.05)。肺动脉主干、组1的左肺动脉干、左肺上叶动脉、段动脉SNR值和CNR值低于组2(Z=-2.45、-2.57、2.09、-3.58,P<0.05;Z =-2.33、2.42、2.07、3.45,P<0.05)。亚段动脉SNR值、CNR值两组间差异无统计学意义(P>0.05)。两名阅片者的评分结果一致性良好(Kappa 值>0.75,P<0.05)。结论 光谱CT肺动脉成像 30 ml低剂量对比剂可以获得良好的肺动脉图像,肺动脉主干管径>30 mm特别是疑诊肺动脉高压的患者肺动脉远端分支显示不佳。
英文摘要:
      Objective Evaluate the image quality of dual-layer spectral detector CT pulmonary angiography with low-dose contrast agents, and explore the influence of pulmonary artery diameter on the image quality. Methods A total of 91 spectral CT pulmonary angiography from March 2022 to August 2022 were retrospectively analyzed. The cases were divided into Group 1 (n=34, main pulmonary artery diameter ≥ 30 mm) and Group 2 (n=57, main pulmonary artery diameter<30 mm). The dosage of contrast agent was 30 ml. The CT attenuation values(CT values), standard deviation(SD), signal-to-noise ratio(SNR),and contrast-to-noise ratio(CNR) values of pulmonary artery from the main trunk to the subsegmental pulmonary artery between two groups were compared. The CT dose index volume(CTDIvol) and dose-length production (DLP) were recorded. Two readers evaluated the image quality using three-point method. The inter-reader agreement was performed by Kappa test. Results The CT values of the pulmonary trunk and left pulmonary artery between two groups was not significantly different (P>0.05). The CT values of the left upper lobe artery, segmental artery, and subsegmental artery in Group 1 were lower than those in Group 2 (t=-2.13,-2.17,Z=-2.33,P<0.05). The SD values of pulmonary trunk and segmental artery in Group 1 were higher than those in Group 2 (t=2.27,Z=-2.23,P<0.05). The SD values of left pulmonary artery, left upper lobe artery, and subsegmental artery between two groups were not significantly different (P>0.05). The SNR and CNR values of main pulmonary trunk, left pulmonary artery, left superior lobar artery, and segmental artery in Group 2 were higher than those in Group 1 (Z=-2.45,-2.57,-2.09,-3.58, P<0.05; Z=-2.33,-2.42,-2.07,-3.45, P<0.05), while these values of the subsegmental artery between two groups were not significantly different (P>0.05). The two readers had good consistency in evaluating image quality (Kappa value>0.75,P<0.05). Conclusions Spectral CT pulmonary angiography with 30 ml contrast agent would generate good quality images. However, the distal pulmonary artery would be poorly revealed when the diameter of main pulmonary artery more than 30mm, especially in patients with suspected pulmonary hypertension.
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