| 张坤,石祥,谢双双,林丽滢,窦亚娜,沈文.利用同源双能CT (SF-DECT)提高儿童腹部图像质量的可行性研究[J].中华放射医学与防护杂志,2023,43(8):639-644 |
| 利用同源双能CT (SF-DECT)提高儿童腹部图像质量的可行性研究 |
| Feasibility of improving the quality of children's abdominal images using split-filter dual-energy CT |
| 投稿时间：2023-02-13 |
| DOI：10.3760/cma.j.cn112271-20230213-00034 |
| 中文关键词: 双能CT 儿童体模 辐射剂量 图像质量 |
| 英文关键词:Dual-energy CT Child phantom Radiation dose Image quality |
| 基金项目:国家自然科学基金（81901710，81873888）；天津市卫生健康科技项目青年人才项目（TJWJ2021QN011，QN20024）；天津市自然科学基金（22JCQNJC00920）；天津市医学重点学科（专科）建设项目（TJYXZDXK-041A）临床试验注册：中国临床试验注册中心，ChiCTR1800019231 |
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| 中文摘要: |
| 目的 评估在儿童腹部检查中，同源双能CT （SF-DECT）是否能在低剂量条件下提高图像质量。方法 采用儿童体模进行初步研究，并于2020年6月至12月期间前瞻性招募20名4~6岁的儿童进行临床验证。分别采用常规单能CT （SECT）和SF-DECT扫描体模和儿童的的腹部区域，比较SF-DECT和SECT在各剂量下（1、2、3和4 mGy） CT值、图像噪声、对比噪声比（CNR）和图像主观评分。结果 在体模研究中，3和4 mGy剂量条件下，与SECT相比，SF-DECT的图像噪声分别降低了18.9%和23.6%，肝脏和肾脏CNR分别最多增加了12.8%和31.9%（Z=3.00、5.17，P<0.001）。在儿童SF-DECT扫描中，随着扫描剂量的增加，图像噪声降低（Z=4.64，P<0.001），肝脏和肾脏CNR增加（Z=3.78、3.39，P<0.001）。在体模研究和患者研究中，SF-DECT扫描图像的主观评分均优于SECT （Z=1.96~3.80，P<0.05）。结论 与SECT相比，SF-DECT能够提高儿童腹部扫描图像质量。该技术在优化儿童腹部CT扫描方面有一定前景，但需要进行深入的临床研究来验证结果。 |
| 英文摘要: |
| Objective To evaluate the effects of split-filter dual-energy CT (SF-DECT) in improving image quality at low doses in the process of abdominal examinations for children.Methods A preliminary study was conducted using child phantoms. Furthermore, 20 children aged 4-6 years were recruited prospectively for clinical validation from June 2020 to December 2020. Conventional single-energy CT (SECT) and SF-DECT were employed to scan the abdominal areas of the phantoms and children. Then, the CT values, image noise, contrast to noise ratios (CNRs), and image subjective scores of SF-DECT and SECT were compared under various doses (1, 2, 3, and 4 mGy).Results For the phantoms under doses of 3 and 4 mGy, SF-DECT decreased the image noise by 18.9% and 23.6%, respectively, and increased the liver and kidney CNRs (CNRliv and CNRkid) by 12.8% and 31.9% at most, respectively, compared to SECT (Z=3.00, 5.17, P < 0.001). For children, SF-DECT decreased image noise (Z=4.64, P < 0.001) and increased CNRliv and CNRkid (Z=3.78, 3.39, P < 0.001). For both the phantoms and the children, the subjective scores of images scanned using the SF-DECT were higher than those scanned using the SECT (Z=1.96-3.80, P < 0.05).Conclusions Compared with SECT, SF-DECT can improve the quality of children's abdominal images. This technique has a certain prospect of optimizing abdominal CT for children. However, it is necessary to conduct in-depth clinical research to verify the result. |
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