| 周本梅,查小英,谭拥,肖鹏,胡明宗.运用ArcCHECK实施宫颈癌超长靶区的剂量验证[J].中华放射医学与防护杂志,2023,43(8):601-606 |
| 运用ArcCHECK实施宫颈癌超长靶区的剂量验证 |
| Applying an ArcCHECK detector to the dose verification for ultra-long target volumes of cervical cancer |
| 投稿时间：2023-02-08 |
| DOI：10.3760/cma.j.cn112271-20230208-00029 |
| 中文关键词: 宫颈癌 超长靶区 剂量验证 γ通过率 |
| 英文关键词:Cervical cancer Ultra-long target volume Dose verification Gamma pass rate |
| 基金项目:宜宾市科技计划项目（2021SF015） |
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| 中文摘要: |
| 目的 初步探讨运用ArcCHECK对宫颈癌超长靶区进行剂量验证的可行性。方法 回顾性选取超长靶区（靶区长度≥ 26cm）和常规靶区（靶区长度< 26cm）的宫颈癌患者各50例，运用容积旋转调强放疗（VMAT）技术完成计划设计，使用ArcCHECK采集验证剂量。在ArcCHECK的中心点处（iso）摆位完成常规靶区组的剂量检测（Short-0 cm），随后将ArcCHECK沿出床方向平移5 cm （iso 1），分别完成超长靶区组（Long-5 cm）和常规靶区组（Short-5 cm）的剂量检测。分析各组计划的几何参数（靶区长度和靶区体积）、机器参数（机器跳数和照射时间），以及在不同检测条件下的γ通过率。结果 超长靶区组的靶区长度、靶区体积、机器跳数和照射时间均大于常规靶区组（t=2.61~18.56，P < 0.05），常规靶区组在iso 1处的γ通过率明显低于iso处的γ通过率（t=2.14~8.17，P < 0.05）。在iso 1处，超长靶区组的γ通过率明显低于常规靶区组（t=-4.70~-2.73，P < 0.01）。各组γ通过率在3%/3 mm和3%/2 mm的标准下均能满足临床需求。结论 摆位中心和靶区长度是影响验证结果的主要因素，对于超长靶区可通过移动摆位中心的方式进行剂量验证，从而确保患者治疗的精确性。 |
| 英文摘要: |
| Objective To explore the feasibility of applying an ArcCHECK detector to the dose verification for ultra-long target volumes of cervical cancer.Methods This study retrospectively selected patients suffering from cervical cancer with ultra-long target volumes (lengths: ≥ 26 cm; 50 cases; the ultra-long target volume group) and conventional target volumes (lengths:< 26 cm; 50 cases; the conventional target volume group). Subsequently, this study designed treatment plans using the Volumetric Modulated Arc Therapy (VMAT) technique and then collected and verified doses using an ArcCHECK detector. The dose detection for the conventional target volume group was performed at the central point of the detector (marked by iso and Short-0 cm). Then, the detector was moved for 5 cm along the bed exit direction (marked by iso 1), followed by the dose verification of the ultra-long target volume group (marked by Long-5 cm) and conventional target volume group (marked by Short-5 cm). The geometric parameters (the length and volume of a target volume), mechanical parameters (machine hop count and the duration of irradiation), and gamma pass rates (GPRs) under different detection conditions of each group were analyzed.Results The target lengths, target volumes, machine hop counts, and irradiation durations of the ultra-long target group were higher than those of the conventional target group (t=2.61-18.56, P < 0.05). For the conventional target group, the GPRs at iso 1 were significantly lower than those at iso (t=2.14-8.17, P < 0.05). Meanwhile, the GPRs at iso 1 of the ultra-long target volume group were significantly lower than those of the conventional target volume group (t=-4.70 to -2.73, P < 0.01). The GPRs of each group met clinical requirements for criteria of both 3%/3 mm and 3%/2 mm.Conclusions The deviation of the positioning center and the length of the target volume serve as primary factors affecting the dose verification result of cervical cancer. For ultra-long target volumes, dose verification can be performed by moving the positioning center, thus ensuring treatment accuracy for cervical cancer patients. |
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