李小亮,孙伟航,李则书,拓飞,彭玄,闵楠,刘建香,孙全富.6家医院碘治疗场所工作人员甲状腺131I活度测量[J].中华放射医学与防护杂志,2022,42(6):448-453
6家医院碘治疗场所工作人员甲状腺131I活度测量
Measurement of 131I activity in thyroid of workers at the place of radioiodine therapy in six hospitals
投稿时间:2021-09-08  
DOI:10.3760/cma.j.cn112271-20210908-00371
中文关键词:  核医学  甲状腺  131I  内照射
英文关键词:Nuclear medicine  Thyroid  131I  Internal exposure
基金项目:
作者单位E-mail
李小亮 中国疾病预防控制中心辐射防护与核安全医学所 辐射防护与核应急中国疾病预防控制中心重点实验室北京 100088  
孙伟航 山东省医学科学院放射医学研究所济南 250001  
李则书 中国疾病预防控制中心辐射防护与核安全医学所 辐射防护与核应急中国疾病预防控制中心重点实验室北京 100088  
拓飞 中国疾病预防控制中心辐射防护与核安全医学所 辐射防护与核应急中国疾病预防控制中心重点实验室北京 100088  
彭玄 中国疾病预防控制中心辐射防护与核安全医学所 辐射防护与核应急中国疾病预防控制中心重点实验室北京 100088  
闵楠 山东省医学科学院放射医学研究所济南 250001  
刘建香 中国疾病预防控制中心辐射防护与核安全医学所 辐射防护与核应急中国疾病预防控制中心重点实验室北京 100088  
孙全富 中国疾病预防控制中心辐射防护与核安全医学所 辐射防护与核应急中国疾病预防控制中心重点实验室北京 100088 sunquanfu@nirp.chinacdc.cn 
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中文摘要:
      目的 调查碘治疗场所工作人员甲状腺131I活度水平及其主要影响因素。方法 采用配额抽样的方法,按照碘治疗场所医院的不同类型,在山西省和山东省共选择6家开展碘治疗的医院,采用直接测量法,对76名碘治疗场所工作人员的甲状腺131I活度进行了测量,并进行内照射剂量估算。结果 共有5家医院的29人甲状腺131I活度高于仪器的探测限,占全部被检测人员的38.16%,其中最高值为2 468.45 Bq,是1名负责手动分装放射性碘的医师。6家医院碘治疗场所工作人员甲状腺131I活度差异无统计学意义(P>0.05),但手动分装131I的医院测量结果高于自动分装的医院,差异有统计学意义(Z=1.75,P<0.01),两家手动分装131I医院的12名碘治疗场所工作人员甲状腺测量结果全部高于探测限,中位数分别为324.59 Bq和331.98 Bq,4家使用自动分装仪的医院测量结果的中位数均低于探测限,甲状腺131I检出率分别为32.61%、25.00%、10.00%和0。对于同一家医院,参与分装131I的医生和保洁人员甲状腺131I活度高于不参与分装的医生,差异有统计学意义(Z=2.44、2.12,P<0.05)。结论 不同碘治疗场所工作人员内照射水平差异较大,使用自动分装仪可有效降低碘治疗场所工作人员内照射水平,应进一步加强碘治疗场所控制区工作人员的内照射监测。
英文摘要:
      Objective To investigate 131I activity in thyroid of workers at the place of radioiodine therapy and its main influencing factors.Methods In terms of the types of hospitals, six hospitals that performed radioiodine therapy procedure were selected by quota sampling in the provinces of Shandong and Shanxi. 131I activity in thyroids of 76 workers at the place of radioiodine therapy was measured directly, and their internal doses were estimated.Results 131I activity in thyroids was found to be above the detection limit for 29 subjects (38.16%) in five hospitals. The maximum value of 131I activity was 2 468.45 Bq for a doctor who was responsible for manual distribution of radioisotopes. In general 131I activities in thyroid of workers at the place of radioiodine therapy of six hospitals were not significantly different (P > 0.05). But the measurement result in the hospitals where radioiodine was distributed manually were significantly higher than that in the hospitals where radioiodine was distributed automatically (Z=1.75, P < 0.01). Thyroid measurement result of 12 workers in two hospitals where radioiodine was distributed manually were all above the detection limit, with medians of 324.59 Bq and 331.98 Bq, respectively. The medians of 131I activities in thyroid of 12 staff in the remaining 4 hospitals were all below the detection limit. The detection frequencies of 131I above dose limit were 32.61%, 25.00%, 10.00% and 0. The measurement result for the doctors who participated in distributing 131I and the relevent cleaners were significantly higher than for the doctors who did not participate in distributing 131I at the same hospital (Z=2.44, 2.12, P < 0.05).Conclusions There was a significant difference in the internal exposure level among workers at the different places of radioiodine therapy. Using automatic loading device could reduce the internal exposure level of the workers at the place of radioiodine therapy. It is necessary to strengthen the radiological protection for workers at the control area of the place of radioiodine therapy.
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