张宇,刘昌盛,郭可磊,彭宙锋,查云飞.胸部低剂量CT在新型冠状病毒疾病患者出院后复查的应用价值[J].中华放射医学与防护杂志,2020,40(10):789-793
胸部低剂量CT在新型冠状病毒疾病患者出院后复查的应用价值
Application value of post-discharge chest low-dose CT for patients with COVID-19
投稿时间:2020-03-30  
DOI:10.3760/cma.j.issn.0254-5098.2020.10.010
中文关键词:  新型冠状病毒肺炎  低剂量  胸部  复查  计算机体层成像
英文关键词:COVID-19  Low dose  Chest  Follow-up  Computed tomography
基金项目:
作者单位E-mail
张宇 武汉大学人民医院放射科 430060  
刘昌盛 武汉大学人民医院放射科 430060  
郭可磊 武汉大学人民医院放射科 430060  
彭宙锋 武汉大学人民医院放射科 430060  
查云飞 武汉大学人民医院放射科 430060 zhayunfei999@126.com 
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中文摘要:
      目的 探讨胸部低剂量CT在新型冠状病毒疾病(COVID-19)患者好转出院后复查应用价值。方法 回顾性分析2020年3月17日至3月25日经武汉大学人民医院治疗出院后的58例COVID-19患者胸部低剂量CT表现,由两名影像医师独立评价CT图像质量,采用5分法进行评分。并计算信噪比(SNR)、背景噪声(SDair)及辐射剂量。结果 出院前常规剂量组和出院后复查低剂量组图像主观评分观察者1和观察者2分别为4.45±0.22、3.88±0.33(P>0.05)和4.37±0.18、3.91±0.35(P>0.05);低剂量组的SNR与SDair分别为4.39±0.95和7.19±2.41,显著低于常规组的5.14±1.06(Z=-5.551,P<0.001)和6.48±1.57(Z=-3.217,P<0.001),图像质量均能满足临床诊断。低剂量组的CT容积剂量指数(CTDIvol)、剂量长度乘积(DLP)及有效剂量(E)分别为(2.41±0.09) mGy、(88.03±5.33) mGy·cm和(1.23±0.17) mSv,均显著低于常规组[(10.53±1.03) mGy,(338.74±34.64) mGy·cm,(4.74±0.48) mSv,Z=-6.568、-6.624、-5.976,P<0.001)。结论 COVID-19患者出院后可采用胸部低剂量CT复查。
英文摘要:
      Objective To explore the value of chest low-dose CT (LDCT) in post-discharge follow-up assessments of patients with coronavirus disease 2019 (COVID-19 ). Methods The chest CT findings of 58 patients with COVID-19 from March 17 to March 25, 2020 at Remin Hospital of Wuhan University were retrospectively analyzed. Two radiologists independently scored the subjective image quality on a 5-point Likert scale. The signal-to-noise ratio (SNR) and SDair of images and the CT radiation dose parameters were calculated, including the CT volume dose index (CTDIvol), dose length product (DLP), and effective radiation dose (E ). Results The subjective image quality scores on CT images obtained before and after discharge by readers 1 and 2, were 4.45±0.22, 3.88±0.33 (P>0.05) and 4.37±0.18, 3.91±0.35 (P>0.05 ), respectively. The SNR and SDair in LDCT after discharge were 4.39±0.95 and 7.19±2.41, which were significantly lower than those in routine chest CT before discharge (5.14±1.06, Z=-5.551, P<0.001; 6.48±1.57, Z=-3.217, P<0.001 ). All of the obtained images were sufficient for diagnosis. The CTDIvol, DLP, and E in LDCT were significantly lower than those in routine CT [(2.41±0.09), (10.53±1.03)mGy, Z=-6.568, P<0.001; (88.03±5.33), (338.74±34.64)mGy·cm, Z=-6.624, P<0.001; and (1.23±0.17), (4.74±0.48)mSv, Z=-5.976, P<0.001 ]. Conclusions Patients with COVID-19 can be followed up with low-dose chest CT after discharge.
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