| 蒋耀军,吴艳,张永高,等.低管电流联合多模型迭代重建技术对腰椎定量CT准确度的应用价值[J].中华放射医学与防护杂志,2018,38(1):59-63.Jiang Yaojun,Wu Yan,Zhang Yonggao,et al.Application of low-tube current using adaptive statistic iterative reconstruction in the accuracy of spinal quantitative CT[J].Chin J Radiol Med Prot,2018,38(1):59-63 |
| 低管电流联合多模型迭代重建技术对腰椎定量CT准确度的应用价值 |
| Application of low-tube current using adaptive statistic iterative reconstruction in the accuracy of spinal quantitative CT |
| 投稿时间：2017-08-02 |
| DOI：10.3760/cma.j.issn.0254-5098.2018.01.013 |
| 中文关键词: 定量CT 骨密度 X射线计算机 辐射剂量 迭代重建 |
| 英文关键词:Quantitative CT Bone mineral density X-ray computed Radiation dosage Iterative reconstruction |
| 基金项目:国家自然科学基金联合基金项目（U1504821） |
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| 中文摘要: |
| 目的 通过模型研究，探讨低mA联合多模型迭代重建对腰椎骨密度（BMD）准确度的可行性。方法 应用GE Revolution原型机，在5种不同的剂量水平（管电压120 kV，管电流40、60、80、100和120 mA），对欧洲腰椎体模（ESP）进行扫描，并分别进行多模型数据迭代重建（ASiR-V）（权重0、20%、40%、60%、80%和100%）。分别在L1、L2和L3正中间置感兴趣区（ROI），测量其CT值、噪声，并计算其对比噪声比（CNR）。采用单因素方差分析比较在不同剂量水平和不同迭代权重比例条件下的骨密度值。结果 容积CT剂量指数（CTDIvol）和剂量长度乘积（DLP）与管电流呈正相关关系（r=1）。在不同辐射剂量、同一迭代权重下，ESP （L1，L2和L3）的BMD差异均无统计学意义（P>0.05）；在相同辐射剂量、不同的迭代权重条件下，ESP （L1，L2和L3）的BMD差异均无统计学意义（P>0.05）。腰椎BMD准确度误差均在6%以内。结论 ESP腰椎BMD进行重复性测量，120 kV、40 mA低剂量条件下，不影响BMD准确度，实现腰椎定量CT （QCT）的准确测量，并显著降低辐射剂量；同时，可以适当增加ASiR-V权重比例，降低图像噪声，提高图像质量。 |
| 英文摘要: |
| Objective To investigate the reproducibility and accuracy of spinal BMD(bone mineral density) by low mA using adaptive statistic iterative reconstruction based on phantom model. Methods European spine phantom (ESP) was scanned with 5 different tube currents (40, 60, 80, 100 and 120 mA) on the GE Revolution prototype. All data were transferred to the quantitative CT (QCT) PRO workstation for measuring the bone mineral density(BMD). And all data were reconstructed using different adaptive statistical iterative reconstruction veo(ASiR-V) weighting percentages from ASiR-V 0 filtered back projection(FBP) to ASiR-V 100%, at interval of 20%. Quantitative measurements of CT value, noise, and contrast noise ratio (CNR) of L1, L2 and L3 were measured in each group. The single-factor analysis of variance (ANOVA) was used to compare the bone mineral density values of different mA and ASiR-V weighting percentages. Results Volume CT dose index(CTDIvol) and dose length product(DLP) were positively correlated with tube current(r=1).The BMD of ESP phantoms had no statistically significant differences among the multi-center lumbar spines L1, L2 and L3 at different doses under the same ASiR-V weighting percentages(P>0.05), as well as at the same dose under different ASiR-V weighting percentages(P>0.05).The error of bone density accuracy was within 6%. Conclusions Low dosage of 120 kV and 40 mA using ASiR-V without affecting the accuracy of BMD has the potential effect to reduce radiation dose without compromising image quality. |
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