许洋,杨彦勇,高福.肠道菌群与肠道辐射损伤的关系及其机制研究进展[J].中华放射医学与防护杂志,2017,37(2):157-160.Xu Yang,Yang Yanyong,Gao Fu.Progresses on mechanism of the relationship between gut microbiota and radiation injuries[J].Chin J Radiol Med Prot,2017,37(2):157-160
肠道菌群与肠道辐射损伤的关系及其机制研究进展
Progresses on mechanism of the relationship between gut microbiota and radiation injuries
投稿时间:2016-09-21  
DOI:10.3760/cma.j.issn.0254-5098.2017.02.014
中文关键词:  肠道菌群  辐射损伤  Toll样受体
英文关键词:Gut microbiota  Radiation injuries  Toll-like receptors
基金项目:
作者单位E-mail
许洋 200433 上海, 第二军医大学海军医学系舰船辐射医学教研室  
杨彦勇 200433 上海, 第二军医大学海军医学系舰船辐射医学教研室  
高福 200433 上海, 第二军医大学海军医学系舰船辐射医学教研室 gaofusmmu@163.com 
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中文摘要:
      近些年,越来越多的研究人员开始重视肠道菌群与人体健康的关系,并试图探讨其在辐射损伤中的作用。越来越多的证据表明,正常的肠道菌群通过Toll样受体、免疫途径和炎症反应等维持人体的健康。改善肠道菌群、调节菌群的平衡已作为治疗某些疾病的手段之一。本文综述肠道菌群与肠道辐射损伤的关系和机制,以期为放射性肠炎及其他疾病的治疗提供理论依据和指导。
英文摘要:
      Recently, researchers have paid attention to the relationship between gut microbiota and human health and attempted to investigate the effect of gut microbiota on radiation injury. More and more evidence showed that normal gut microbiota could maintain human health through Toll-like receptors, immune system and inflammatory reaction. Improvements of gut microbiota spectrum and its balance have become an effective strategy for the treatment of certain diseases. This paper reviewed the relationship between gut microbiota and radiation injury and underlying mechanisms, in order to provide novel theoretical evidence and guideline for the therapy of radiation enteritis and other diseases.
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