| 顾恒乐,王昊,陈华,徐志勇.准直器角度对胸上段食管癌容积旋转调强放疗剂量的影响[J].中华放射医学与防护杂志,2016,36(7):505-508 |
| 准直器角度对胸上段食管癌容积旋转调强放疗剂量的影响 |
| Dosimetric impact of collimator angles on VMAT planning for upper thoracic esophageal carcinoma |
| 投稿时间：2016-03-01 |
| DOI：10.3760/cma.j.issn.0254-5098.2016.07.006 |
| 中文关键词: 容积旋转调强放疗 准直器 角度 食管癌 |
| 英文关键词:Volumetric modulated arc therapy Collimator Angle Esophageal carcinoma |
| 基金项目: |
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| 中文摘要: |
| 目的 研究不同准直器角度对胸上段食管癌病例的剂量影响。方法 选择8例胸上段食管癌病例作为研究对象，每个病例设计准直器角度为0°、5°、10°、15°、20°、25°、30°、35°、40°和45°的10个容积旋转调强放疗（VMAT）计划，比较不同角度下的靶区和危及器官各剂量参数以及总机器跳数。结果 通过比较10组不同准直器角度计划的各项指标结果，选取整体表现最佳的20°组和临床上使用较多的0°及45°组进行分析，显示正常组织全肺V10、V15和V30差异有统计学意义（F=5.328、8.033、28.424，P < 0.05），脊髓Dmax和总机器跳数MU差异有统计学意义（F=9.608、4.464，P < 0.05）。其他指标差异无统计学意义（P > 0.05）。结论 在胸上段食管癌VMAT计划设计时，选择合适的准直器角度可以保证靶区剂量分布，减少危及器官受量，能更好地保护正常组织，并提高治疗效率。 |
| 英文摘要: |
| Objective To evaluate the dosimetric impact from collimator angles during the VMAT planning for upper thoracic esophageal carcinoma. Methods VMAT plans for 8 cases of upper thoracic esophageal were studied. Ten different plans with respective collimator angles (0, 5, 10, 15, 20, 25, 30, 35, 40, 45 degrees) were determined for each case, and the treatment planning parameters were compared. Results The 20 degree group represented with best performance, and 0 and 45 degree group were most frequently used in clinical practice. Statistical analysis shown that among these groups, V10,V15 and V30 of total lung were significantly different (F=5.328, 8.033, 28.424, P < 0.05), and differences of maximal dose of spinal cord and total MU were also significant (F=9.608, 4.464,P < 0.05). Conclusions A proper collimator angle is important in VMAT planning for upper thoracic esophageal and may lead to optimal results. |
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